Platelet concentrate increases bone ingrowth into porous hydroxyapatite
(2002) In Orthopedics 25(2). p.72-169- Abstract
- Platelets contain growth factors that are believed to stimulate early fracture repair. Autologous platelets can be sequestered, concentrated, and mixed with thrombin to yield a so-called autologous growth factor gel, which might enhance bone repair or bone graft incorporation. The effect of this platelet concentrate on total tissue and bone ingrowth into porous coralline hydroxyapatite was studied in a bone chamber rat model. Chambers with the platelet concentrate showed a significant increase in bone and total tissue ingrowth distance compared to untreated controls, indicating a platelet concentrate might enhance the clinical performance of porous hydroxyapatite in bone replacement.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/106604
- author
- Siebrecht, Maikel A N ; De Rooij, Philippe P ; Arm, Douglas M ; Olsson, Martin L LU and Aspenberg, Per LU
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Orthopedics
- volume
- 25
- issue
- 2
- pages
- 72 - 169
- publisher
- Slack Inc
- external identifiers
-
- scopus:0036184972
- pmid:11871379
- ISSN
- 1938-2367
- language
- English
- LU publication?
- no
- id
- 35381e66-92fe-4519-bf88-e8187a6a77d1 (old id 106604)
- date added to LUP
- 2016-04-01 11:55:58
- date last changed
- 2022-03-05 08:35:52
@article{35381e66-92fe-4519-bf88-e8187a6a77d1, abstract = {{Platelets contain growth factors that are believed to stimulate early fracture repair. Autologous platelets can be sequestered, concentrated, and mixed with thrombin to yield a so-called autologous growth factor gel, which might enhance bone repair or bone graft incorporation. The effect of this platelet concentrate on total tissue and bone ingrowth into porous coralline hydroxyapatite was studied in a bone chamber rat model. Chambers with the platelet concentrate showed a significant increase in bone and total tissue ingrowth distance compared to untreated controls, indicating a platelet concentrate might enhance the clinical performance of porous hydroxyapatite in bone replacement.}}, author = {{Siebrecht, Maikel A N and De Rooij, Philippe P and Arm, Douglas M and Olsson, Martin L and Aspenberg, Per}}, issn = {{1938-2367}}, language = {{eng}}, number = {{2}}, pages = {{72--169}}, publisher = {{Slack Inc}}, series = {{Orthopedics}}, title = {{Platelet concentrate increases bone ingrowth into porous hydroxyapatite}}, volume = {{25}}, year = {{2002}}, }