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Riktlinjer för handläggning av patienter med pankreascancer

Ihse, Ingemar LU ; Permert, Johan; Andersson, Roland LU ; Borgström, Anders LU ; Dawiskiba, Sigmund LU ; Enander, Lars Krister; Glimelius, Bengt; Hafström, Larsolof; Haglund, Ulf and Larsson, Jörgen, et al. (2002) In Läkartidningen 99(15). p.1676-1683
Abstract
The incidence of pancreatic cancer has fallen during the last ten years in Sweden. Early signs and symptoms of the disease are still undiscovered and when diagnosis is made the disease is incurable in most patients. Transabdominal ultrasonography is the first-line imaging test followed by spiral computed tomography (CT) and magnetic resonance imaging (MRI) if required for definite diagnosis. Spiral CT is also the imaging test of choice for assessment of resectability of the tumor. Surgical removal of the tumor is the only chance of cure. Markedly improved hospital mortality after pancreaticoduodenectomy is reported and an association between hospital volume and outcome of the operation has been established. Longterm survival after... (More)
The incidence of pancreatic cancer has fallen during the last ten years in Sweden. Early signs and symptoms of the disease are still undiscovered and when diagnosis is made the disease is incurable in most patients. Transabdominal ultrasonography is the first-line imaging test followed by spiral computed tomography (CT) and magnetic resonance imaging (MRI) if required for definite diagnosis. Spiral CT is also the imaging test of choice for assessment of resectability of the tumor. Surgical removal of the tumor is the only chance of cure. Markedly improved hospital mortality after pancreaticoduodenectomy is reported and an association between hospital volume and outcome of the operation has been established. Longterm survival after attempted curative resection continues to be dismal, however. Adjuvant treatment should not be given outside clinical studies. Palliative treatment has improved thanks to progress in the field of endoscopy, interventional radiology and in management of pain and nutrition. Palliative chemotherapy should only be given selectively outside clinical studies. Radiotherapy has no proven effects on survival. Special pancreatic cancer treatment teams with catchment areas of 2-4 million inhabitants are recommended by international authorities. (Less)
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organization
alternative title
Guidelines for management of patients with pancreatic cancer
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Randomized Controlled Trials, Survival Rate, Radiotherapy, Preoperative Care, Postoperative Care, Practice Guidelines, Pancreaticoduodenectomy, Pancreatic Neoplasms : therapy, Pancreatic Neoplasms : mortality, Pancreatic Neoplasms : diagnosis, Palliative Care, Meta-Analysis, Incidence, Evidence-Based Medicine, Human, English Abstract, Sweden : epidemiology, Adjuvant, Analgesia : methods, Chemotherapy, Controlled Clinical Trials
in
Läkartidningen
volume
99
issue
15
pages
1676 - 1683
publisher
Swedish Medical Association
external identifiers
  • scopus:0037061839
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
2ff987e7-3022-4e28-b1b0-7892135b861c (old id 108374)
alternative location
http://ltarkiv.lakartidningen.se/artNo24593
date added to LUP
2007-07-20 10:47:59
date last changed
2017-01-01 06:44:24
@article{2ff987e7-3022-4e28-b1b0-7892135b861c,
  abstract     = {The incidence of pancreatic cancer has fallen during the last ten years in Sweden. Early signs and symptoms of the disease are still undiscovered and when diagnosis is made the disease is incurable in most patients. Transabdominal ultrasonography is the first-line imaging test followed by spiral computed tomography (CT) and magnetic resonance imaging (MRI) if required for definite diagnosis. Spiral CT is also the imaging test of choice for assessment of resectability of the tumor. Surgical removal of the tumor is the only chance of cure. Markedly improved hospital mortality after pancreaticoduodenectomy is reported and an association between hospital volume and outcome of the operation has been established. Longterm survival after attempted curative resection continues to be dismal, however. Adjuvant treatment should not be given outside clinical studies. Palliative treatment has improved thanks to progress in the field of endoscopy, interventional radiology and in management of pain and nutrition. Palliative chemotherapy should only be given selectively outside clinical studies. Radiotherapy has no proven effects on survival. Special pancreatic cancer treatment teams with catchment areas of 2-4 million inhabitants are recommended by international authorities.},
  author       = {Ihse, Ingemar and Permert, Johan and Andersson, Roland and Borgström, Anders and Dawiskiba, Sigmund and Enander, Lars Krister and Glimelius, Bengt and Hafström, Larsolof and Haglund, Ulf and Larsson, Jörgen and Lindell, Gert and Olmarker, Anne and von Rosen, Anette and Svanvik, Joar and Svensson, Jan-Olof and Thune, Anders and Tranberg, Karl-Göran},
  issn         = {0023-7205},
  keyword      = {Randomized Controlled Trials,Survival Rate,Radiotherapy,Preoperative Care,Postoperative Care,Practice Guidelines,Pancreaticoduodenectomy,Pancreatic Neoplasms : therapy,Pancreatic Neoplasms : mortality,Pancreatic Neoplasms : diagnosis,Palliative Care,Meta-Analysis,Incidence,Evidence-Based Medicine,Human,English Abstract,Sweden : epidemiology,Adjuvant,Analgesia : methods,Chemotherapy,Controlled Clinical Trials},
  language     = {swe},
  number       = {15},
  pages        = {1676--1683},
  publisher    = {Swedish Medical Association},
  series       = {Läkartidningen},
  title        = {Riktlinjer för handläggning av patienter med pankreascancer},
  volume       = {99},
  year         = {2002},
}