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Morphology of inter-atrial conduction routes in patients with atrial fibrillation.

Platonov, Pyotr LU ; Mitrofanova, L B; Chireikin, L V and Olsson, S B (2002) In Europace 4(2). p.183-192
Abstract
BACKGROUND: Inter-atrial conduction disturbance is associated with the presence of atrial fibrillation (AF), although little is known about the anatomy of the inter-atrial connections. METHODS AND RESULTS: Twenty-seven hearts from in-hospital deaths were examined and stratified in two groups with regard to their history of AF. Measurements of atrial weight were performed after excising the atria at the level of the atrioventricular valve plane and separation from the inter-atrial septum (IAS). In addition, in 15 of 27 hearts (seven AF, eight non-AF) the IAS was sliced into 10 microm thick parallel histological sections at intervals of 1 mm starting at the valve plane and ending at the atrial roof. The sections were stained with van... (More)
BACKGROUND: Inter-atrial conduction disturbance is associated with the presence of atrial fibrillation (AF), although little is known about the anatomy of the inter-atrial connections. METHODS AND RESULTS: Twenty-seven hearts from in-hospital deaths were examined and stratified in two groups with regard to their history of AF. Measurements of atrial weight were performed after excising the atria at the level of the atrioventricular valve plane and separation from the inter-atrial septum (IAS). In addition, in 15 of 27 hearts (seven AF, eight non-AF) the IAS was sliced into 10 microm thick parallel histological sections at intervals of 1 mm starting at the valve plane and ending at the atrial roof. The sections were stained with van Gieson's stain. The variable morphology of the anterior and posterior inter-atrial connective muscle bundles is described. The total number of inter-atrial connections varied from 1 to 5. The anterior route (Bachmann's bundle) was not found in seven of 15 specimens. CONCLUSION: Inter-atrial connections are characterized by substantial variability in morphology and in the distribution of bundles. This may account for part of the variable susceptibility to AF. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Europace
volume
4
issue
2
pages
183 - 192
publisher
Oxford University Press
external identifiers
  • wos:000176743400013
  • pmid:12135252
  • scopus:0036556443
ISSN
1532-2092
DOI
10.1053/eupc.2002.0221
language
English
LU publication?
yes
id
6184d779-8e92-4fe6-b006-9a7cb6af44cc (old id 109546)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12135252&dopt=Abstract
date added to LUP
2007-07-02 12:42:39
date last changed
2017-09-10 03:44:03
@article{6184d779-8e92-4fe6-b006-9a7cb6af44cc,
  abstract     = {BACKGROUND: Inter-atrial conduction disturbance is associated with the presence of atrial fibrillation (AF), although little is known about the anatomy of the inter-atrial connections. METHODS AND RESULTS: Twenty-seven hearts from in-hospital deaths were examined and stratified in two groups with regard to their history of AF. Measurements of atrial weight were performed after excising the atria at the level of the atrioventricular valve plane and separation from the inter-atrial septum (IAS). In addition, in 15 of 27 hearts (seven AF, eight non-AF) the IAS was sliced into 10 microm thick parallel histological sections at intervals of 1 mm starting at the valve plane and ending at the atrial roof. The sections were stained with van Gieson's stain. The variable morphology of the anterior and posterior inter-atrial connective muscle bundles is described. The total number of inter-atrial connections varied from 1 to 5. The anterior route (Bachmann's bundle) was not found in seven of 15 specimens. CONCLUSION: Inter-atrial connections are characterized by substantial variability in morphology and in the distribution of bundles. This may account for part of the variable susceptibility to AF.},
  author       = {Platonov, Pyotr and Mitrofanova, L B and Chireikin, L V and Olsson, S B},
  issn         = {1532-2092},
  language     = {eng},
  number       = {2},
  pages        = {183--192},
  publisher    = {Oxford University Press},
  series       = {Europace},
  title        = {Morphology of inter-atrial conduction routes in patients with atrial fibrillation.},
  url          = {http://dx.doi.org/10.1053/eupc.2002.0221},
  volume       = {4},
  year         = {2002},
}