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Diffusion-weighted imaging of brain metastases: their potential to be misinterpreted as focal ischaemic lesions.

Geijer, Bo LU and Holtås, S (2002) In Neuroradiology 44(7). p.568-573
Abstract
Small focal ischaemic brain lesions are said to be easy to identify in the acute stage and to differentiate from older lesions using diffusion-weighted imaging (DWI). Brain metastases are common and the aim of this study was to evaluate the risk of misinterpretation as ischaemic lesions in a standard MRI protocol for clinical stroke. Of 26 patients investigated with MRI for possible metastases, 12 did have metastatic brain lesions, including most of the common tumours. On a 1.5 tesla imager, we obtained DWI, plus T2- and T1-weighted images, the latter before and after triple-dose contrast medium. Well-circumscribed brain lesions with a decreased apparent diffusion coefficient and a slightly or moderately increased signal on T2-weighted... (More)
Small focal ischaemic brain lesions are said to be easy to identify in the acute stage and to differentiate from older lesions using diffusion-weighted imaging (DWI). Brain metastases are common and the aim of this study was to evaluate the risk of misinterpretation as ischaemic lesions in a standard MRI protocol for clinical stroke. Of 26 patients investigated with MRI for possible metastases, 12 did have metastatic brain lesions, including most of the common tumours. On a 1.5 tesla imager, we obtained DWI, plus T2- and T1-weighted images, the latter before and after triple-dose contrast medium. Well-circumscribed brain lesions with a decreased apparent diffusion coefficient and a slightly or moderately increased signal on T2-weighted images were found in patients with metastases from a small-cell bronchial carcinoma and a pulmonary adenocarcinoma. The same features were also found in metastases from a breast carcinoma but the lesions were surrounded by oedema. With a standard DWI protocol, the features of common brain metastases may overlap with those of small acute and subacute ischaemic lesions. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Neuroradiology
volume
44
issue
7
pages
568 - 573
publisher
Springer Verlag
external identifiers
  • pmid:12136357
  • wos:000177370200002
  • scopus:0036940019
ISSN
1432-1920
DOI
10.1007/s00234-002-0792-0
language
English
LU publication?
yes
id
98d652ae-9aed-4f09-ac83-43fb98eaea45 (old id 109559)
alternative location
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12136357&dopt=Abstract
date added to LUP
2007-07-18 13:51:36
date last changed
2017-10-01 03:52:19
@article{98d652ae-9aed-4f09-ac83-43fb98eaea45,
  abstract     = {Small focal ischaemic brain lesions are said to be easy to identify in the acute stage and to differentiate from older lesions using diffusion-weighted imaging (DWI). Brain metastases are common and the aim of this study was to evaluate the risk of misinterpretation as ischaemic lesions in a standard MRI protocol for clinical stroke. Of 26 patients investigated with MRI for possible metastases, 12 did have metastatic brain lesions, including most of the common tumours. On a 1.5 tesla imager, we obtained DWI, plus T2- and T1-weighted images, the latter before and after triple-dose contrast medium. Well-circumscribed brain lesions with a decreased apparent diffusion coefficient and a slightly or moderately increased signal on T2-weighted images were found in patients with metastases from a small-cell bronchial carcinoma and a pulmonary adenocarcinoma. The same features were also found in metastases from a breast carcinoma but the lesions were surrounded by oedema. With a standard DWI protocol, the features of common brain metastases may overlap with those of small acute and subacute ischaemic lesions.},
  author       = {Geijer, Bo and Holtås, S},
  issn         = {1432-1920},
  language     = {eng},
  number       = {7},
  pages        = {568--573},
  publisher    = {Springer Verlag},
  series       = {Neuroradiology},
  title        = {Diffusion-weighted imaging of brain metastases: their potential to be misinterpreted as focal ischaemic lesions.},
  url          = {http://dx.doi.org/10.1007/s00234-002-0792-0},
  volume       = {44},
  year         = {2002},
}