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Cytogenetic abnormalities in a hemangiopericytoma of the spleen.

Hallén, Magnus LU ; Parada, Luis A ; Gorunova, Ludmila LU ; Pålsson, Birger LU ; Dictor, Michael LU and Johansson, Bertil LU (2002) In Cancer Genetics and Cytogenetics 136(1). p.62-65
Abstract
To date, only 16 cytogenetically abnormal hemangiopericytomas (HP) have been reported. Despite this low number, some characteristic karyotypic features have already emerged: most HP are near-diploid and breakpoints in 12q13, 12q24, and 19q13 seem to be common, with t(12;19)(q13;q13) being a recurrent translocation. Here, we report the first case of a probably benign splenic HP with chromosomal abnormalities. The abnormal karyotype was 47,XX,t(5;22;11)(q31;q11;q13),+10. None of these abnormalities have previously been reported in HP, suggesting that the karyotypic pattern of splenic HP may differ from soft tissue HP.
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Contribution to journal
publication status
published
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keywords
Male, Karyotyping, Immunohistochemistry, Human, Hemangiopericytoma : genetics, Female, Cytogenetic Analysis, Case Report, Chromosome Aberrations, Splenic Neoplasms : genetics
in
Cancer Genetics and Cytogenetics
volume
136
issue
1
pages
62 - 65
publisher
Elsevier
external identifiers
  • wos:000177326500011
  • scopus:0036648444
ISSN
0165-4608
DOI
10.1016/S0165-4608(01)00664-1
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Surgery (Lund) (013009000), Division of Clinical Genetics (013022003), Pathology, (Lund) (013030000), Surgery Research Unit (013242220)
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5d352a1f-9507-4ad0-92ab-3efd16cea585 (old id 109784)
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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12165454&dopt=Abstract
date added to LUP
2016-04-01 15:26:49
date last changed
2020-01-12 18:29:32
@article{5d352a1f-9507-4ad0-92ab-3efd16cea585,
  abstract     = {To date, only 16 cytogenetically abnormal hemangiopericytomas (HP) have been reported. Despite this low number, some characteristic karyotypic features have already emerged: most HP are near-diploid and breakpoints in 12q13, 12q24, and 19q13 seem to be common, with t(12;19)(q13;q13) being a recurrent translocation. Here, we report the first case of a probably benign splenic HP with chromosomal abnormalities. The abnormal karyotype was 47,XX,t(5;22;11)(q31;q11;q13),+10. None of these abnormalities have previously been reported in HP, suggesting that the karyotypic pattern of splenic HP may differ from soft tissue HP.},
  author       = {Hallén, Magnus and Parada, Luis A and Gorunova, Ludmila and Pålsson, Birger and Dictor, Michael and Johansson, Bertil},
  issn         = {0165-4608},
  language     = {eng},
  number       = {1},
  pages        = {62--65},
  publisher    = {Elsevier},
  series       = {Cancer Genetics and Cytogenetics},
  title        = {Cytogenetic abnormalities in a hemangiopericytoma of the spleen.},
  url          = {http://dx.doi.org/10.1016/S0165-4608(01)00664-1},
  doi          = {10.1016/S0165-4608(01)00664-1},
  volume       = {136},
  year         = {2002},
}