Parental alcohol use disorder and offspring marital outcomes
(2019) In Addiction 114(1). p.81-91- Abstract
Aims: We tested whether parental alcohol use disorder (AUD) predicted adult offspring's likelihood of marriage and marriage to an AUD-affected spouse; whether effects differed as a function of the sex or number of affected parents; and whether they were robust to confounders. Design: Sex-stratified Cox and logistic regression models. Setting: Sweden. Participants: A total of 1 171 070 individuals (51.40% male) born 1965–75. Measurements: Obtained from legal, medical and pharmacy registries. Predictor was parent AUD. Outcomes were marriage and spouse AUD. Adjustments included offspring birth year and AUD; and parental education, marriage, divorce, criminal behavior and drug abuse. Findings: Male and female offspring of AUD-affected... (More)
Aims: We tested whether parental alcohol use disorder (AUD) predicted adult offspring's likelihood of marriage and marriage to an AUD-affected spouse; whether effects differed as a function of the sex or number of affected parents; and whether they were robust to confounders. Design: Sex-stratified Cox and logistic regression models. Setting: Sweden. Participants: A total of 1 171 070 individuals (51.40% male) born 1965–75. Measurements: Obtained from legal, medical and pharmacy registries. Predictor was parent AUD. Outcomes were marriage and spouse AUD. Adjustments included offspring birth year and AUD; and parental education, marriage, divorce, criminal behavior and drug abuse. Findings: Male and female offspring of AUD-affected parents were more likely to marry at younger ages (< 25), illustrative unadjusted hazard ratio (HR)age 20 = 1.22 (1.17, 1.28) and 1.34 (1.20, 1.39) and were less likely to marry at older ages (> 25), HRage 30 = 0.79 (0.78, 0.81) and 0.82 (0.81, 0.84). Parental AUD was associated with higher odds of having an affected spouse for males and females, odds ratio (OR) = 1.47 (1.38, 1.57) and 1.63 (1.56, 1.70). Effects were more pronounced for those with two versus one AUD-affected parent and adjustments attenuated effects negligibly. Daughters of affected mothers (versus fathers) were more likely to have AUD-affected husbands, OR = 1.68 (1.54, 1.84) versus 1.56 (1.48, 1.64), while there was no difference in sons. Conclusions: In Sweden, parental alcohol use disorder (AUD) is associated with a higher probability of marriage at younger ages, a lower probability of marriage at older ages and a higher likelihood of marriage to an affected spouse compared with no parental AUD. Most of these effects become stronger when the number of AUD-affected parents increases from one to two, and most effects hold after controlling for parents’ socio-economic status, marital history, other externalizing disorders and offspring's own AUD status. Daughters of affected mothers are more likely to have an affected spouse.
(Less)
- author
- Salvatore, Jessica E. ; Larsson Lönn, Sara LU ; Long, Elizabeth C. ; Sundquist, Jan LU ; Kendler, Kenneth S. LU ; Sundquist, Kristina LU and Edwards, Alexis C. LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adult children of alcoholics, age-dependent effects, marital, marriage, parental alcohol use disorder, spousal alcohol use disorder
- in
- Addiction
- volume
- 114
- issue
- 1
- pages
- 81 - 91
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85052965650
- pmid:30063276
- ISSN
- 0965-2140
- DOI
- 10.1111/add.14405
- language
- English
- LU publication?
- yes
- id
- 10d6e626-0850-47e8-a23b-7e59c8ca7a46
- date added to LUP
- 2018-10-23 12:18:12
- date last changed
- 2024-06-10 20:46:11
@article{10d6e626-0850-47e8-a23b-7e59c8ca7a46,
abstract = {{<p>Aims: We tested whether parental alcohol use disorder (AUD) predicted adult offspring's likelihood of marriage and marriage to an AUD-affected spouse; whether effects differed as a function of the sex or number of affected parents; and whether they were robust to confounders. Design: Sex-stratified Cox and logistic regression models. Setting: Sweden. Participants: A total of 1 171 070 individuals (51.40% male) born 1965–75. Measurements: Obtained from legal, medical and pharmacy registries. Predictor was parent AUD. Outcomes were marriage and spouse AUD. Adjustments included offspring birth year and AUD; and parental education, marriage, divorce, criminal behavior and drug abuse. Findings: Male and female offspring of AUD-affected parents were more likely to marry at younger ages (< 25), illustrative unadjusted hazard ratio (HR)<sub>age 20</sub> = 1.22 (1.17, 1.28) and 1.34 (1.20, 1.39) and were less likely to marry at older ages (> 25), HR<sub>age 30</sub> = 0.79 (0.78, 0.81) and 0.82 (0.81, 0.84). Parental AUD was associated with higher odds of having an affected spouse for males and females, odds ratio (OR) = 1.47 (1.38, 1.57) and 1.63 (1.56, 1.70). Effects were more pronounced for those with two versus one AUD-affected parent and adjustments attenuated effects negligibly. Daughters of affected mothers (versus fathers) were more likely to have AUD-affected husbands, OR = 1.68 (1.54, 1.84) versus 1.56 (1.48, 1.64), while there was no difference in sons. Conclusions: In Sweden, parental alcohol use disorder (AUD) is associated with a higher probability of marriage at younger ages, a lower probability of marriage at older ages and a higher likelihood of marriage to an affected spouse compared with no parental AUD. Most of these effects become stronger when the number of AUD-affected parents increases from one to two, and most effects hold after controlling for parents’ socio-economic status, marital history, other externalizing disorders and offspring's own AUD status. Daughters of affected mothers are more likely to have an affected spouse.</p>}},
author = {{Salvatore, Jessica E. and Larsson Lönn, Sara and Long, Elizabeth C. and Sundquist, Jan and Kendler, Kenneth S. and Sundquist, Kristina and Edwards, Alexis C.}},
issn = {{0965-2140}},
keywords = {{Adult children of alcoholics; age-dependent effects; marital; marriage; parental alcohol use disorder; spousal alcohol use disorder}},
language = {{eng}},
number = {{1}},
pages = {{81--91}},
publisher = {{Wiley-Blackwell}},
series = {{Addiction}},
title = {{Parental alcohol use disorder and offspring marital outcomes}},
url = {{http://dx.doi.org/10.1111/add.14405}},
doi = {{10.1111/add.14405}},
volume = {{114}},
year = {{2019}},
}