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Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results

Lindholm, C-E; Kjellén, Elisabeth LU ; Landberg, Torsten LU ; Nilsson, Per LU and Persson, B (1982) In Acta radiologica. Oncology 21(4). p.241-254
Abstract
The combination of microwave-induced (2450 MHz) hyperthermia and ionizing radiation was used in 7 patients with superficial malignant tumours, which were considered refractory to other therapy. A newly developed heating system was used, allowing for a maintained temperature at the master probe of 42.5 degrees C +/- 0.5 degrees C during 45 min, but temperature measurements at multiple sites showed a marked variation. This preliminary series indicates that the combination of hyperthermia and ionizing radiation may be useful, the response rate (complete or partial) being 8 of 8 evaluable lesions. Even previously heavily irradiated sites responded. Technical improvements are highly needed to allow for controlled heating of any tissue volume.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta radiologica. Oncology
volume
21
issue
4
pages
241 - 254
publisher
Taylor & Francis
external identifiers
  • pmid:6293267
  • scopus:84907108391
ISSN
0349-652X
DOI
10.3109/02841868209134013
language
English
LU publication?
yes
id
c515124b-a7c2-4289-b3e6-9b3d74e19077 (old id 1102920)
date added to LUP
2008-08-13 13:45:40
date last changed
2017-01-01 06:57:45
@article{c515124b-a7c2-4289-b3e6-9b3d74e19077,
  abstract     = {The combination of microwave-induced (2450 MHz) hyperthermia and ionizing radiation was used in 7 patients with superficial malignant tumours, which were considered refractory to other therapy. A newly developed heating system was used, allowing for a maintained temperature at the master probe of 42.5 degrees C +/- 0.5 degrees C during 45 min, but temperature measurements at multiple sites showed a marked variation. This preliminary series indicates that the combination of hyperthermia and ionizing radiation may be useful, the response rate (complete or partial) being 8 of 8 evaluable lesions. Even previously heavily irradiated sites responded. Technical improvements are highly needed to allow for controlled heating of any tissue volume.},
  author       = {Lindholm, C-E and Kjellén, Elisabeth and Landberg, Torsten and Nilsson, Per and Persson, B},
  issn         = {0349-652X},
  language     = {eng},
  number       = {4},
  pages        = {241--254},
  publisher    = {Taylor & Francis},
  series       = {Acta radiologica. Oncology},
  title        = {Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results},
  url          = {http://dx.doi.org/10.3109/02841868209134013},
  volume       = {21},
  year         = {1982},
}