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Failure to detect immune complexes in the secondary stage of pityriasis rosea

Mobacken, H; Bjursten, Lars Magnus LU ; Löwhagen, G B and Nilsson, L Å (1983) In Archives for Dermatological Research 275(2). p.92-94
Abstract
Thirty-three patients with pityriasis rosea were studied with regard to the possible presence of circulating and cutaneously deposited immune complexes. The levels of circulating immune complexes, determined by a solid-phase C1q-binding assay, were not different from those of healthy control individuals. The levels were similar in samples obtained during the initial and during the remission stages of the disease. Cutaneous deposits of immunoglobulin and/or complement were found in only 5 of 33 patients. This study does not support of concept that circulating immune complexes are important for the development of the secondary skin lesions in pityriasis rosea.
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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Immune complexes, Pityriasis rosea
in
Archives for Dermatological Research
volume
275
issue
2
pages
92 - 94
publisher
Springer
external identifiers
  • pmid:6870348
  • scopus:0020611938
ISSN
1432-069X
DOI
10.1007/BF00412881
language
English
LU publication?
no
id
c042f39c-a507-44f2-8642-0b7a882fdde8 (old id 1103012)
date added to LUP
2008-08-13 11:19:08
date last changed
2017-08-06 04:31:49
@article{c042f39c-a507-44f2-8642-0b7a882fdde8,
  abstract     = {Thirty-three patients with pityriasis rosea were studied with regard to the possible presence of circulating and cutaneously deposited immune complexes. The levels of circulating immune complexes, determined by a solid-phase C1q-binding assay, were not different from those of healthy control individuals. The levels were similar in samples obtained during the initial and during the remission stages of the disease. Cutaneous deposits of immunoglobulin and/or complement were found in only 5 of 33 patients. This study does not support of concept that circulating immune complexes are important for the development of the secondary skin lesions in pityriasis rosea.},
  author       = {Mobacken, H and Bjursten, Lars Magnus and Löwhagen, G B and Nilsson, L Å},
  issn         = {1432-069X},
  keyword      = {Immune complexes,Pityriasis rosea},
  language     = {eng},
  number       = {2},
  pages        = {92--94},
  publisher    = {Springer},
  series       = {Archives for Dermatological Research},
  title        = {Failure to detect immune complexes in the secondary stage of pityriasis rosea},
  url          = {http://dx.doi.org/10.1007/BF00412881},
  volume       = {275},
  year         = {1983},
}