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Lipoteichoic acid is the major cell wall component responsible for surface hydrophobicity of group A streptococci

Miörner, Håkan LU ; Johansson, Göte and Kronvall, Göran (1983) In Infection and Immunity 39(1). p.336-343
Abstract
The contribution of lipoteichoic acid (LTA) to the hydrophobic surface properties of group A streptococci was investigated in aqueous dextran-polyethylene glycol two-phase systems. Enzymatic digestions were performed to characterize the hydrophobic surface structure. The results obtained indicated that LTA is a major factor responsible for the hydrophobic character of the cell surface of group A streptococci. This was further supported by the similarity of partition in polymer two-phase systems between whole group A streptococci and tritiated LTA extracted from a group A streptococcal strain. Surface LTA was also determined on intact organisms by a new method measuring the adsorption of antibodies to LTA to the bacterial surface. A... (More)
The contribution of lipoteichoic acid (LTA) to the hydrophobic surface properties of group A streptococci was investigated in aqueous dextran-polyethylene glycol two-phase systems. Enzymatic digestions were performed to characterize the hydrophobic surface structure. The results obtained indicated that LTA is a major factor responsible for the hydrophobic character of the cell surface of group A streptococci. This was further supported by the similarity of partition in polymer two-phase systems between whole group A streptococci and tritiated LTA extracted from a group A streptococcal strain. Surface LTA was also determined on intact organisms by a new method measuring the adsorption of antibodies to LTA to the bacterial surface. A correlation was found between the content of surface LTA and the hydrophobicity of the group A streptococci. We conclude that surface-associated LTA is the major factor determining surface hydrophobicity of group A streptococci. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Infection and Immunity
volume
39
issue
1
pages
336 - 343
publisher
American Society for Microbiology
external identifiers
  • pmid:6337099
  • scopus:0020695696
ISSN
1098-5522
language
English
LU publication?
yes
id
503d3c14-1d01-44f9-8be7-4f0e5a3f993f (old id 1103072)
alternative location
http://iai.asm.org/cgi/reprint/39/1/336
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=347944&blobtype=pdf
date added to LUP
2008-08-13 09:24:47
date last changed
2017-10-22 03:34:38
@article{503d3c14-1d01-44f9-8be7-4f0e5a3f993f,
  abstract     = {The contribution of lipoteichoic acid (LTA) to the hydrophobic surface properties of group A streptococci was investigated in aqueous dextran-polyethylene glycol two-phase systems. Enzymatic digestions were performed to characterize the hydrophobic surface structure. The results obtained indicated that LTA is a major factor responsible for the hydrophobic character of the cell surface of group A streptococci. This was further supported by the similarity of partition in polymer two-phase systems between whole group A streptococci and tritiated LTA extracted from a group A streptococcal strain. Surface LTA was also determined on intact organisms by a new method measuring the adsorption of antibodies to LTA to the bacterial surface. A correlation was found between the content of surface LTA and the hydrophobicity of the group A streptococci. We conclude that surface-associated LTA is the major factor determining surface hydrophobicity of group A streptococci.},
  author       = {Miörner, Håkan and Johansson, Göte and Kronvall, Göran},
  issn         = {1098-5522},
  language     = {eng},
  number       = {1},
  pages        = {336--343},
  publisher    = {American Society for Microbiology},
  series       = {Infection and Immunity},
  title        = {Lipoteichoic acid is the major cell wall component responsible for surface hydrophobicity of group A streptococci},
  volume       = {39},
  year         = {1983},
}