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Chlorhexidine for prevention of neonatal colonization with group B streptococci. II. Chlorhexidine concentrations and recovery of group B streptococci following vaginal washing in pregnant women

Dykes, Anna-Karin LU ; Kvist Christensen, Karen; Christensen, Poul and Kahlmeter, Gunnar (1983) In European Journal of Obstetrics, Gynecology, and Reproductive Biology 16(3). p.167-172
Abstract
The effect of a single washing of the urogenital tract with 0.5 g/l chlorhexidine was studied in 6 women in weeks 38-40 of pregnancy, among whom 5 were carriers of group B streptococci in urethra and/or cervix. The chlorhexidine concentrations varied between 25 and 200 mg/l during the first hour after washing in 5 of the 6 women, whereas one patient showed concentrations below 25 mg/l. With the exception of one patient, all individuals showed concentrations less than 25 mg/l at 3-24 h after washing. A clear suppression of the number of colony-forming units of GBS was already apparent after 60 min and was still evident 6 h after chlorhexidine washing.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
group B streptococci, Chlorhexidine, vaginal colonization
in
European Journal of Obstetrics, Gynecology, and Reproductive Biology
volume
16
issue
3
pages
167 - 172
publisher
Elsevier
external identifiers
  • pmid:6363152
  • scopus:0021025660
ISSN
0301-2115
DOI
10.1016/0028-2243(83)90096-5
language
English
LU publication?
yes
id
cb78a6b2-3db9-4d5f-8137-58116146b480 (old id 1103140)
date added to LUP
2008-08-13 08:45:41
date last changed
2017-01-01 04:52:49
@article{cb78a6b2-3db9-4d5f-8137-58116146b480,
  abstract     = {The effect of a single washing of the urogenital tract with 0.5 g/l chlorhexidine was studied in 6 women in weeks 38-40 of pregnancy, among whom 5 were carriers of group B streptococci in urethra and/or cervix. The chlorhexidine concentrations varied between 25 and 200 mg/l during the first hour after washing in 5 of the 6 women, whereas one patient showed concentrations below 25 mg/l. With the exception of one patient, all individuals showed concentrations less than 25 mg/l at 3-24 h after washing. A clear suppression of the number of colony-forming units of GBS was already apparent after 60 min and was still evident 6 h after chlorhexidine washing.},
  author       = {Dykes, Anna-Karin and Kvist Christensen, Karen and Christensen, Poul and Kahlmeter, Gunnar},
  issn         = {0301-2115},
  keyword      = {group B streptococci,Chlorhexidine,vaginal colonization},
  language     = {eng},
  number       = {3},
  pages        = {167--172},
  publisher    = {Elsevier},
  series       = {European Journal of Obstetrics, Gynecology, and Reproductive Biology},
  title        = {Chlorhexidine for prevention of neonatal colonization with group B streptococci. II. Chlorhexidine concentrations and recovery of group B streptococci following vaginal washing in pregnant women},
  url          = {http://dx.doi.org/10.1016/0028-2243(83)90096-5},
  volume       = {16},
  year         = {1983},
}