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Chlorhexidine for prevention of neonatal colonization with group B streptococci. II. Chlorhexidine concentrations and recovery of group B streptococci following vaginal washing in pregnant women

Dykes, Anna-Karin LU ; Kvist Christensen, Karen ; Christensen, Poul and Kahlmeter, Gunnar (1983) In European Journal of Obstetrics, Gynecology, and Reproductive Biology 16(3). p.167-172
Abstract
The effect of a single washing of the urogenital tract with 0.5 g/l chlorhexidine was studied in 6 women in weeks 38-40 of pregnancy, among whom 5 were carriers of group B streptococci in urethra and/or cervix. The chlorhexidine concentrations varied between 25 and 200 mg/l during the first hour after washing in 5 of the 6 women, whereas one patient showed concentrations below 25 mg/l. With the exception of one patient, all individuals showed concentrations less than 25 mg/l at 3-24 h after washing. A clear suppression of the number of colony-forming units of GBS was already apparent after 60 min and was still evident 6 h after chlorhexidine washing.
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
group B streptococci, Chlorhexidine, vaginal colonization
in
European Journal of Obstetrics, Gynecology, and Reproductive Biology
volume
16
issue
3
pages
167 - 172
publisher
Elsevier
external identifiers
  • pmid:6363152
  • scopus:0021025660
ISSN
0301-2115
DOI
10.1016/0028-2243(83)90096-5
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Nursing (Closed 2012) (013065000), Department of Obstetrics and Gynaecology (Lund) (013018000), Division of Medical Microbiology (013250400)
id
cb78a6b2-3db9-4d5f-8137-58116146b480 (old id 1103140)
date added to LUP
2016-04-01 12:08:40
date last changed
2021-09-19 04:22:07
@article{cb78a6b2-3db9-4d5f-8137-58116146b480,
  abstract     = {{The effect of a single washing of the urogenital tract with 0.5 g/l chlorhexidine was studied in 6 women in weeks 38-40 of pregnancy, among whom 5 were carriers of group B streptococci in urethra and/or cervix. The chlorhexidine concentrations varied between 25 and 200 mg/l during the first hour after washing in 5 of the 6 women, whereas one patient showed concentrations below 25 mg/l. With the exception of one patient, all individuals showed concentrations less than 25 mg/l at 3-24 h after washing. A clear suppression of the number of colony-forming units of GBS was already apparent after 60 min and was still evident 6 h after chlorhexidine washing.}},
  author       = {{Dykes, Anna-Karin and Kvist Christensen, Karen and Christensen, Poul and Kahlmeter, Gunnar}},
  issn         = {{0301-2115}},
  keywords     = {{group B streptococci; Chlorhexidine; vaginal colonization}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{167--172}},
  publisher    = {{Elsevier}},
  series       = {{European Journal of Obstetrics, Gynecology, and Reproductive Biology}},
  title        = {{Chlorhexidine for prevention of neonatal colonization with group B streptococci. II. Chlorhexidine concentrations and recovery of group B streptococci following vaginal washing in pregnant women}},
  url          = {{http://dx.doi.org/10.1016/0028-2243(83)90096-5}},
  doi          = {{10.1016/0028-2243(83)90096-5}},
  volume       = {{16}},
  year         = {{1983}},
}