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Sleep-walking shifts and cerebral blood flow in stable preterm infants

Greisen, Gorm; Hellström-Westas, Lena LU ; Lou, Hans; Rosén, Ingmar LU and Svenningsen, Niels (1985) In Pediatric Research 19(11). p.1156-1159
Abstract
Cerebral blood flow was estimated on 60 occasions in 15 well infants, 29-34 wk of gestational age, 5-17 days after birth, using 133-Xenon clearance after intravenous injection. The sleep state of the infants was determined by biparietal electroencephalography, clinical observation, and tracings of heart rate and respiration. Blood flow was 22% higher in the 11 estimations made during wakefulness, when compared to the 17 estimations made during quiet sleep. There was no difference between blood flow in active and quiet sleep. Also there was no difference between blood flow during periods of trace alternant and blood flow during periods of continuous electroencephalographic activity. It is suggested that flow-metabolism coupling is present... (More)
Cerebral blood flow was estimated on 60 occasions in 15 well infants, 29-34 wk of gestational age, 5-17 days after birth, using 133-Xenon clearance after intravenous injection. The sleep state of the infants was determined by biparietal electroencephalography, clinical observation, and tracings of heart rate and respiration. Blood flow was 22% higher in the 11 estimations made during wakefulness, when compared to the 17 estimations made during quiet sleep. There was no difference between blood flow in active and quiet sleep. Also there was no difference between blood flow during periods of trace alternant and blood flow during periods of continuous electroencephalographic activity. It is suggested that flow-metabolism coupling is present in stable, preterm infants. The absence of an increase in cerebral blood flow during active sleep as compared with quiet sleep suggests that the neurophysiologic and neurometabolic mechanisms of rapid eye movement sleep are not yet fully developed in preterm infants. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pediatric Research
volume
19
issue
11
pages
1156 - 1159
publisher
International Pediatric Foundation Inc.
external identifiers
  • pmid:4069823
ISSN
1530-0447
language
English
LU publication?
yes
id
19df8a6e-d3ff-4199-af7b-6d3a5901ca29 (old id 1103343)
date added to LUP
2008-08-11 12:29:22
date last changed
2016-04-15 19:44:57
@article{19df8a6e-d3ff-4199-af7b-6d3a5901ca29,
  abstract     = {Cerebral blood flow was estimated on 60 occasions in 15 well infants, 29-34 wk of gestational age, 5-17 days after birth, using 133-Xenon clearance after intravenous injection. The sleep state of the infants was determined by biparietal electroencephalography, clinical observation, and tracings of heart rate and respiration. Blood flow was 22% higher in the 11 estimations made during wakefulness, when compared to the 17 estimations made during quiet sleep. There was no difference between blood flow in active and quiet sleep. Also there was no difference between blood flow during periods of trace alternant and blood flow during periods of continuous electroencephalographic activity. It is suggested that flow-metabolism coupling is present in stable, preterm infants. The absence of an increase in cerebral blood flow during active sleep as compared with quiet sleep suggests that the neurophysiologic and neurometabolic mechanisms of rapid eye movement sleep are not yet fully developed in preterm infants.},
  author       = {Greisen, Gorm and Hellström-Westas, Lena and Lou, Hans and Rosén, Ingmar and Svenningsen, Niels},
  issn         = {1530-0447},
  language     = {eng},
  number       = {11},
  pages        = {1156--1159},
  publisher    = {International Pediatric Foundation Inc.},
  series       = {Pediatric Research},
  title        = {Sleep-walking shifts and cerebral blood flow in stable preterm infants},
  volume       = {19},
  year         = {1985},
}