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Specificity of Fc receptors induced by herpes simplex virus type 1: comparison of immunoglobulin G from different animal species

Johansson, Hugo LU ; Myhre, Erling LU and Blomberg, Jonas (1985) In Journal of Virology 56(2). p.489-494
Abstract
Cells infected with herpes simplex virus type 1 (HSV-1) express a cell surface receptor able to bind the Fc portion of immunoglobulin G (IgG). Of the four human IgG subclasses, the HSV-1 Fc receptor, like staphylococcal protein A, binds to all except IgG3. In this paper, we describe the binding of a number of animal IgG and IgG subclass molecules to HSV-1-infected cells and compare this binding to that of protein A. Although only few representatives from each animal order were tested, we found that IgG from Carnivora and Rodentia did not bind or bound only slightly to the HSV-1 receptor, whereas IgG from Primates, Lagomorpha, and Artiodactyla bound well. This pattern was clearly different from the species spectrum of IgG binding of protein... (More)
Cells infected with herpes simplex virus type 1 (HSV-1) express a cell surface receptor able to bind the Fc portion of immunoglobulin G (IgG). Of the four human IgG subclasses, the HSV-1 Fc receptor, like staphylococcal protein A, binds to all except IgG3. In this paper, we describe the binding of a number of animal IgG and IgG subclass molecules to HSV-1-infected cells and compare this binding to that of protein A. Although only few representatives from each animal order were tested, we found that IgG from Carnivora and Rodentia did not bind or bound only slightly to the HSV-1 receptor, whereas IgG from Primates, Lagomorpha, and Artiodactyla bound well. This pattern was clearly different from the species spectrum of IgG binding of protein A. Differences between the two receptors were also found when animal IgG subclasses were tested. The pronounced differences in affinity for the HSV-1 Fc receptor between immunoglobulins from, for example, mouse and rabbit may influence the interpretation of animal studies with this virus. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Virology
volume
56
issue
2
pages
489 - 494
publisher
American Society for Microbiology
external identifiers
  • pmid:2997471
  • scopus:0022409810
ISSN
1098-5514
language
English
LU publication?
yes
id
c46a65d6-1acb-47ba-baac-faabc5662efe (old id 1103388)
alternative location
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=252604&blobtype=pdf
date added to LUP
2008-08-11 13:03:27
date last changed
2017-07-30 04:30:36
@article{c46a65d6-1acb-47ba-baac-faabc5662efe,
  abstract     = {Cells infected with herpes simplex virus type 1 (HSV-1) express a cell surface receptor able to bind the Fc portion of immunoglobulin G (IgG). Of the four human IgG subclasses, the HSV-1 Fc receptor, like staphylococcal protein A, binds to all except IgG3. In this paper, we describe the binding of a number of animal IgG and IgG subclass molecules to HSV-1-infected cells and compare this binding to that of protein A. Although only few representatives from each animal order were tested, we found that IgG from Carnivora and Rodentia did not bind or bound only slightly to the HSV-1 receptor, whereas IgG from Primates, Lagomorpha, and Artiodactyla bound well. This pattern was clearly different from the species spectrum of IgG binding of protein A. Differences between the two receptors were also found when animal IgG subclasses were tested. The pronounced differences in affinity for the HSV-1 Fc receptor between immunoglobulins from, for example, mouse and rabbit may influence the interpretation of animal studies with this virus.},
  author       = {Johansson, Hugo and Myhre, Erling and Blomberg, Jonas},
  issn         = {1098-5514},
  language     = {eng},
  number       = {2},
  pages        = {489--494},
  publisher    = {American Society for Microbiology},
  series       = {Journal of Virology},
  title        = {Specificity of Fc receptors induced by herpes simplex virus type 1: comparison of immunoglobulin G from different animal species},
  volume       = {56},
  year         = {1985},
}