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Computed tomography in the diagnosis and treatment of mediastinal abnormalities in children

Ivancev, Krassi LU ; Halldorsdottir, A; Laurin, Sven LU ; Sandström, Staffan LU ; Békássy, Albert LU ; Garwicz, Stanislaw LU and Wiebe, Thomas LU (1988) In Acta Radiologica 29(1). p.115-120
Abstract
Thirty-one children with mediastinal abnormalities--14 malignant lymphomas, 4 other primary malignancies, one metastatic and 12 benign lesions--were examined one or several times using CT, which proved to be effective especially for cysts (5 patients), ductus arteriosus aneurysm (2 patients), and intrathoracic liver (one patient). It also supplied important diagnostic information regarding the extent of disease in malignant thymoma (one patient), in neurinoma (one patient), and in Hodgkin's lymphoma (5 patients). It was found to be useful in the monitoring of treatment of patients with lymphomas, in which a small residue, probably a fibrotic remnant, was invariably seen after completion of chemotherapy and irradiation. It was concluded... (More)
Thirty-one children with mediastinal abnormalities--14 malignant lymphomas, 4 other primary malignancies, one metastatic and 12 benign lesions--were examined one or several times using CT, which proved to be effective especially for cysts (5 patients), ductus arteriosus aneurysm (2 patients), and intrathoracic liver (one patient). It also supplied important diagnostic information regarding the extent of disease in malignant thymoma (one patient), in neurinoma (one patient), and in Hodgkin's lymphoma (5 patients). It was found to be useful in the monitoring of treatment of patients with lymphomas, in which a small residue, probably a fibrotic remnant, was invariably seen after completion of chemotherapy and irradiation. It was concluded that when the residue was enlarged, the possibility of relapse and even thymic hyperplasia should be considered. However, if CT was performed under general anaesthesia pseudo-widening of the anterior mediastinum could simulate recurrence. Surgical biopsy was found to be necessary in these cases because fine-needle aspiration biopsy was unsuccessful. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Radiologica
volume
29
issue
1
pages
115 - 120
publisher
John Wiley & Sons
external identifiers
  • pmid:2964832
  • scopus:0023864205
ISSN
1600-0455
language
English
LU publication?
yes
id
fdf5597c-ebfb-41af-af76-e6b6b9fbc949 (old id 1104087)
date added to LUP
2008-08-07 10:14:04
date last changed
2017-01-01 07:26:10
@article{fdf5597c-ebfb-41af-af76-e6b6b9fbc949,
  abstract     = {Thirty-one children with mediastinal abnormalities--14 malignant lymphomas, 4 other primary malignancies, one metastatic and 12 benign lesions--were examined one or several times using CT, which proved to be effective especially for cysts (5 patients), ductus arteriosus aneurysm (2 patients), and intrathoracic liver (one patient). It also supplied important diagnostic information regarding the extent of disease in malignant thymoma (one patient), in neurinoma (one patient), and in Hodgkin's lymphoma (5 patients). It was found to be useful in the monitoring of treatment of patients with lymphomas, in which a small residue, probably a fibrotic remnant, was invariably seen after completion of chemotherapy and irradiation. It was concluded that when the residue was enlarged, the possibility of relapse and even thymic hyperplasia should be considered. However, if CT was performed under general anaesthesia pseudo-widening of the anterior mediastinum could simulate recurrence. Surgical biopsy was found to be necessary in these cases because fine-needle aspiration biopsy was unsuccessful.},
  author       = {Ivancev, Krassi and Halldorsdottir, A and Laurin, Sven and Sandström, Staffan and Békássy, Albert and Garwicz, Stanislaw and Wiebe, Thomas},
  issn         = {1600-0455},
  language     = {eng},
  number       = {1},
  pages        = {115--120},
  publisher    = {John Wiley & Sons},
  series       = {Acta Radiologica},
  title        = {Computed tomography in the diagnosis and treatment of mediastinal abnormalities in children},
  volume       = {29},
  year         = {1988},
}