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Comparison of low dose nicotinamide versus benzamide, administered per os, as radiosensitizers in a C3H mammary carcinoma

Kjellén, Elisabeth LU ; Pero, Ronald LU and Nilsson, Per LU (1988) In Radiotherapy and Oncology 12(4). p.327-331
Abstract
We have evaluated if any differences in tumor radiosensitization exist between the two adenosine diphosphate ribosyl transferase (ADPRT) inhibitors nicotinamide and benzamide at fractionated low doses. A significant radiosensitizing effect with nicotinamide at a 10 mg/kg per day dose was found in the tumor model used. We found, however, no radiosensitizing effect with benzamide given according to this schedule.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Radiosensitization, in vivo, C3H-tumor, Benzamide, Nicotinamide
in
Radiotherapy and Oncology
volume
12
issue
4
pages
327 - 331
publisher
Elsevier
external identifiers
  • pmid:2973086
  • scopus:0023770760
ISSN
1879-0887
DOI
10.1016/0167-8140(88)90022-9
language
English
LU publication?
yes
id
e00a9852-7a46-4889-88d0-0f04c1b0d076 (old id 1104104)
date added to LUP
2008-08-07 14:06:12
date last changed
2017-01-01 04:55:46
@article{e00a9852-7a46-4889-88d0-0f04c1b0d076,
  abstract     = {We have evaluated if any differences in tumor radiosensitization exist between the two adenosine diphosphate ribosyl transferase (ADPRT) inhibitors nicotinamide and benzamide at fractionated low doses. A significant radiosensitizing effect with nicotinamide at a 10 mg/kg per day dose was found in the tumor model used. We found, however, no radiosensitizing effect with benzamide given according to this schedule.},
  author       = {Kjellén, Elisabeth and Pero, Ronald and Nilsson, Per},
  issn         = {1879-0887},
  keyword      = {Radiosensitization,in vivo,C3H-tumor,Benzamide,Nicotinamide},
  language     = {eng},
  number       = {4},
  pages        = {327--331},
  publisher    = {Elsevier},
  series       = {Radiotherapy and Oncology},
  title        = {Comparison of low dose nicotinamide versus benzamide, administered per os, as radiosensitizers in a C3H mammary carcinoma},
  url          = {http://dx.doi.org/10.1016/0167-8140(88)90022-9},
  volume       = {12},
  year         = {1988},
}