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The effects of pneumatic antishock garments in the treatment of critical abdominal injuries in rats

Åberg, T; Steen, Stig LU ; Vagianos, C; Walther, Bruno LU ; Zoucas, E and Bengmark, Stig LU (1988) In Journal of Trauma 28(6). p.772-778
Abstract
Thirty rats were subjected to a standardized critical aortic injury and divided into six groups. In addition to controls, the animals were treated with a pneumatic antishock garment (PASG), massive intravenous or intra-aortic saline infusion, or PASG in combination with either massive intravenous or intra-aortic saline infusion. Twenty-six rats were subjected to a standardized hepatic injury and divided into four groups. In addition to controls, the animals were treated with PASG, massive intravenous saline infusion, or PASG in combination with massive intravenous saline infusion. These animals were allowed to bleed for 5 minutes before the treatment was started. The treatment with PASG alone prolonged the median survival time... (More)
Thirty rats were subjected to a standardized critical aortic injury and divided into six groups. In addition to controls, the animals were treated with a pneumatic antishock garment (PASG), massive intravenous or intra-aortic saline infusion, or PASG in combination with either massive intravenous or intra-aortic saline infusion. Twenty-six rats were subjected to a standardized hepatic injury and divided into four groups. In addition to controls, the animals were treated with PASG, massive intravenous saline infusion, or PASG in combination with massive intravenous saline infusion. These animals were allowed to bleed for 5 minutes before the treatment was started. The treatment with PASG alone prolonged the median survival time significantly from 7 min in the control group to greater than 120 min in the PASG group in rats with an aortic injury and from 33 to greater than 120 min in rats with a hepatic injury. Intravenous infusion of saline did not prolong the median survival time. Intravenous infusion in combination with PASG did not have any positive effects on median survival time or median mean aortic pressure and failed to prolong the median survival time significantly in rats with a liver injury, as six out of eight animals developed a lethal pulmonary edema. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Trauma
volume
28
issue
6
pages
772 - 778
publisher
Lippincott Williams and Wilkins
external identifiers
  • pmid:3385819
  • scopus:0023684773
ISSN
0022-5282
language
English
LU publication?
yes
id
d3090ccd-6f79-49b7-ae53-b47c70997e10 (old id 1104375)
date added to LUP
2008-08-08 09:36:13
date last changed
2017-05-07 04:23:34
@article{d3090ccd-6f79-49b7-ae53-b47c70997e10,
  abstract     = {Thirty rats were subjected to a standardized critical aortic injury and divided into six groups. In addition to controls, the animals were treated with a pneumatic antishock garment (PASG), massive intravenous or intra-aortic saline infusion, or PASG in combination with either massive intravenous or intra-aortic saline infusion. Twenty-six rats were subjected to a standardized hepatic injury and divided into four groups. In addition to controls, the animals were treated with PASG, massive intravenous saline infusion, or PASG in combination with massive intravenous saline infusion. These animals were allowed to bleed for 5 minutes before the treatment was started. The treatment with PASG alone prolonged the median survival time significantly from 7 min in the control group to greater than 120 min in the PASG group in rats with an aortic injury and from 33 to greater than 120 min in rats with a hepatic injury. Intravenous infusion of saline did not prolong the median survival time. Intravenous infusion in combination with PASG did not have any positive effects on median survival time or median mean aortic pressure and failed to prolong the median survival time significantly in rats with a liver injury, as six out of eight animals developed a lethal pulmonary edema.},
  author       = {Åberg, T and Steen, Stig and Vagianos, C and Walther, Bruno and Zoucas, E and Bengmark, Stig},
  issn         = {0022-5282},
  language     = {eng},
  number       = {6},
  pages        = {772--778},
  publisher    = {Lippincott Williams and Wilkins},
  series       = {Journal of Trauma},
  title        = {The effects of pneumatic antishock garments in the treatment of critical abdominal injuries in rats},
  volume       = {28},
  year         = {1988},
}