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Platelet aggregation on peritoneal tube grafts and double velour grafts in the inferior vena cava of the pig

Ribbe, Else LU ; Norgren, Lars LU ; Thörne, Johan LU ; Jönsson, Bo-Anders LU and Strand, Sven-Erik LU (1988) In British Journal of Surgery 75(1). p.81-85
Abstract
In 14 pigs the infrarenal vena cava was replaced with a peritoneal tube graft or a collagen-coated double velour graft. With 111In-labelled platelets dynamic in vivo imaging of platelet aggregation over the graft was carried out using a scintillation camera. After removal, the grafts were examined by autoradiography for an evaluation of the platelet aggregation pattern. Measurements of activity in different regions of the grafts were also performed. The results indicated low activity uptakes both in vivo and in vitro. The dynamic study did not show any uniform increase of activity content 1-3 h postoperatively, in any of the groups. During the period 2-3 h postoperatively no increasing activity accumulation was found. Hemashield Microvel... (More)
In 14 pigs the infrarenal vena cava was replaced with a peritoneal tube graft or a collagen-coated double velour graft. With 111In-labelled platelets dynamic in vivo imaging of platelet aggregation over the graft was carried out using a scintillation camera. After removal, the grafts were examined by autoradiography for an evaluation of the platelet aggregation pattern. Measurements of activity in different regions of the grafts were also performed. The results indicated low activity uptakes both in vivo and in vitro. The dynamic study did not show any uniform increase of activity content 1-3 h postoperatively, in any of the groups. During the period 2-3 h postoperatively no increasing activity accumulation was found. Hemashield Microvel grafts had an uptake of 0.19 per cent of the total activity while the corresponding figure for peritoneal tube grafts was 0.17 per cent. The activity distribution on different parts of the grafts indicated lower accumulation on the Hemashield graft surfaces than in the anastomoses, while the accumulation was higher on the graft surface of peritoneal tube grafts. The autoradiographical findings supported this indication. In conclusion, low platelet aggregation was found with both dynamic in vivo imaging and in vitro activity measurements on both peritoneal tube grafts and collagen-coated double velour grafts. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Peritoneum • Dacron, inferior vena cava, platelets, indium, vascular surgery
in
British Journal of Surgery
volume
75
issue
1
pages
81 - 85
publisher
John Wiley & Sons
external identifiers
  • scopus:0023863276
ISSN
1365-2168
DOI
10.1002/bjs.1800750129
language
English
LU publication?
yes
id
8ec83492-d7db-4ace-b1ef-c3a4ff8a6604 (old id 1104465)
date added to LUP
2008-08-08 11:33:39
date last changed
2017-01-01 05:17:57
@article{8ec83492-d7db-4ace-b1ef-c3a4ff8a6604,
  abstract     = {In 14 pigs the infrarenal vena cava was replaced with a peritoneal tube graft or a collagen-coated double velour graft. With 111In-labelled platelets dynamic in vivo imaging of platelet aggregation over the graft was carried out using a scintillation camera. After removal, the grafts were examined by autoradiography for an evaluation of the platelet aggregation pattern. Measurements of activity in different regions of the grafts were also performed. The results indicated low activity uptakes both in vivo and in vitro. The dynamic study did not show any uniform increase of activity content 1-3 h postoperatively, in any of the groups. During the period 2-3 h postoperatively no increasing activity accumulation was found. Hemashield Microvel grafts had an uptake of 0.19 per cent of the total activity while the corresponding figure for peritoneal tube grafts was 0.17 per cent. The activity distribution on different parts of the grafts indicated lower accumulation on the Hemashield graft surfaces than in the anastomoses, while the accumulation was higher on the graft surface of peritoneal tube grafts. The autoradiographical findings supported this indication. In conclusion, low platelet aggregation was found with both dynamic in vivo imaging and in vitro activity measurements on both peritoneal tube grafts and collagen-coated double velour grafts.},
  author       = {Ribbe, Else and Norgren, Lars and Thörne, Johan and Jönsson, Bo-Anders and Strand, Sven-Erik},
  issn         = {1365-2168},
  keyword      = {Peritoneum • Dacron,inferior vena cava,platelets,indium,vascular surgery},
  language     = {eng},
  number       = {1},
  pages        = {81--85},
  publisher    = {John Wiley & Sons},
  series       = {British Journal of Surgery},
  title        = {Platelet aggregation on peritoneal tube grafts and double velour grafts in the inferior vena cava of the pig},
  url          = {http://dx.doi.org/10.1002/bjs.1800750129},
  volume       = {75},
  year         = {1988},
}