Interaction between hydrogen peroxide and titanium: a possible role in the biocompatibility of titanium
(1989) In Biomaterials 10(2). p.118-120- Abstract
- Hydroxyl radicals formed from hydrogen peroxide during an inflammatory response are potent agents for cellular deterioration. The behaviour of implanted material in terms of its ability to sustain or stop free radical formation may be therefore very important. In vitro studies of titanium which is known to be biocompatible and osseointegrates into human bone were carried out. In our model studies, the production of free radicals from H2O2 at Ti and TiO2 surfaces was measured by spin trapping techniques. Our findings suggest that there is no sustained hydroxyl radical production at a titanium (oxide) surface. We propose that this is due to the quenching of the Fenton reaction through both trapping and oxidation of superoxide radicals in a... (More)
- Hydroxyl radicals formed from hydrogen peroxide during an inflammatory response are potent agents for cellular deterioration. The behaviour of implanted material in terms of its ability to sustain or stop free radical formation may be therefore very important. In vitro studies of titanium which is known to be biocompatible and osseointegrates into human bone were carried out. In our model studies, the production of free radicals from H2O2 at Ti and TiO2 surfaces was measured by spin trapping techniques. Our findings suggest that there is no sustained hydroxyl radical production at a titanium (oxide) surface. We propose that this is due to the quenching of the Fenton reaction through both trapping and oxidation of superoxide radicals in a TiOOH adduct. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1104489
- author
- Tengvall, Pentti ; Elwing, Hans ; Sjöqvist, Lars ; Lundström, Ingemar and Bjursten, Lars Magnus LU
- publishing date
- 1989
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Titanium, hydrogen peroxide, oxygen radicals, biocompatibility
- in
- Biomaterials
- volume
- 10
- issue
- 2
- pages
- 118 - 120
- publisher
- Elsevier
- external identifiers
-
- pmid:2706298
- scopus:0024598059
- ISSN
- 1878-5905
- DOI
- 10.1016/0142-9612(89)90043-4
- language
- English
- LU publication?
- no
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Bioimplant Research (013242910)
- id
- b5041be7-34b1-46aa-9f1a-75e6fb3438e8 (old id 1104489)
- date added to LUP
- 2016-04-01 12:12:20
- date last changed
- 2021-09-26 03:33:53
@article{b5041be7-34b1-46aa-9f1a-75e6fb3438e8,
abstract = {{Hydroxyl radicals formed from hydrogen peroxide during an inflammatory response are potent agents for cellular deterioration. The behaviour of implanted material in terms of its ability to sustain or stop free radical formation may be therefore very important. In vitro studies of titanium which is known to be biocompatible and osseointegrates into human bone were carried out. In our model studies, the production of free radicals from H2O2 at Ti and TiO2 surfaces was measured by spin trapping techniques. Our findings suggest that there is no sustained hydroxyl radical production at a titanium (oxide) surface. We propose that this is due to the quenching of the Fenton reaction through both trapping and oxidation of superoxide radicals in a TiOOH adduct.}},
author = {{Tengvall, Pentti and Elwing, Hans and Sjöqvist, Lars and Lundström, Ingemar and Bjursten, Lars Magnus}},
issn = {{1878-5905}},
keywords = {{Titanium; hydrogen peroxide; oxygen radicals; biocompatibility}},
language = {{eng}},
number = {{2}},
pages = {{118--120}},
publisher = {{Elsevier}},
series = {{Biomaterials}},
title = {{Interaction between hydrogen peroxide and titanium: a possible role in the biocompatibility of titanium}},
url = {{http://dx.doi.org/10.1016/0142-9612(89)90043-4}},
doi = {{10.1016/0142-9612(89)90043-4}},
volume = {{10}},
year = {{1989}},
}