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Experience with percutaneous titanium implants in the head and neck: a clinical and histological study

Holgers, Kajsa-Mia; Bjursten, Lars Magnus LU ; Thomsen, Peter; Ericson, Lars E and Tjellström, Anders (1989) In Journal of Investigative Surgery 2(1). p.7-16
Abstract
Percutaneous implants have been associated with numerous problems. However, by using skin-penetrating, bone-anchored titanium implants, developed by Professor Branemark at the Department of Anatomy, University of Goteborg, good long-term results have been observed. These implants have been in clinical use for anchorage of bone-conducting hearing aids and facial prostheses since 1977 and 1979, respectively. The total number of implants is approximately 700. Less than 4% of the observations have shown significant irritation. Biopsies from 33 patients were collected for histological studies. In the irritated skin there was an increased number of inflammatory cells, mainly polymorphonuclear cells, B-cells, and plasma cells but not T-cells.... (More)
Percutaneous implants have been associated with numerous problems. However, by using skin-penetrating, bone-anchored titanium implants, developed by Professor Branemark at the Department of Anatomy, University of Goteborg, good long-term results have been observed. These implants have been in clinical use for anchorage of bone-conducting hearing aids and facial prostheses since 1977 and 1979, respectively. The total number of implants is approximately 700. Less than 4% of the observations have shown significant irritation. Biopsies from 33 patients were collected for histological studies. In the irritated skin there was an increased number of inflammatory cells, mainly polymorphonuclear cells, B-cells, and plasma cells but not T-cells. This suggests a response directed against exogenous agents rather than an allergic reaction against the implant per se. (Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
implants, titanium, percutaneous, clinical, histology, histochemistry
in
Journal of Investigative Surgery
volume
2
issue
1
pages
7 - 16
publisher
Taylor & Francis
external identifiers
  • pmid:2487400
  • scopus:0024949626
ISSN
0894-1939
DOI
10.3109/08941938909016500
language
English
LU publication?
no
id
1ed36be1-9bfb-4d51-8ce7-a2d9dc7ff92a (old id 1104494)
date added to LUP
2008-08-06 09:14:52
date last changed
2017-08-06 03:41:14
@article{1ed36be1-9bfb-4d51-8ce7-a2d9dc7ff92a,
  abstract     = {Percutaneous implants have been associated with numerous problems. However, by using skin-penetrating, bone-anchored titanium implants, developed by Professor Branemark at the Department of Anatomy, University of Goteborg, good long-term results have been observed. These implants have been in clinical use for anchorage of bone-conducting hearing aids and facial prostheses since 1977 and 1979, respectively. The total number of implants is approximately 700. Less than 4% of the observations have shown significant irritation. Biopsies from 33 patients were collected for histological studies. In the irritated skin there was an increased number of inflammatory cells, mainly polymorphonuclear cells, B-cells, and plasma cells but not T-cells. This suggests a response directed against exogenous agents rather than an allergic reaction against the implant per se.},
  author       = {Holgers, Kajsa-Mia and Bjursten, Lars Magnus and Thomsen, Peter and Ericson, Lars E and Tjellström, Anders},
  issn         = {0894-1939},
  keyword      = {implants,titanium,percutaneous,clinical,histology,histochemistry},
  language     = {eng},
  number       = {1},
  pages        = {7--16},
  publisher    = {Taylor & Francis},
  series       = {Journal of Investigative Surgery},
  title        = {Experience with percutaneous titanium implants in the head and neck: a clinical and histological study},
  url          = {http://dx.doi.org/10.3109/08941938909016500},
  volume       = {2},
  year         = {1989},
}