Use of ciprofloxacin in patients undergoing transurethral prostatic surgery
(1989) In Scandinavian Journal of Infectious Diseases. Supplementum 60. p.104-107- Abstract
- The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection and compared with that of controls without antibiotic (Group III). Both regimens significantly reduced the frequency of post-operative bacteriuria (p less than 0.01) and of severe infectious complications (p = 0.004) compared to the controls. Both regimens were equally effective in preventing peri-operative and post-operative acquisition of bacteriuria in patients without bacteriuria at surgery. In patients with bacteriuria before surgery, bacteriuria was found post-operatively in 35% in Group I and in 9% in Group II (p = 0.012), but in 82% of the patients in Group III. Ciprofloxacin... (More)
- The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection and compared with that of controls without antibiotic (Group III). Both regimens significantly reduced the frequency of post-operative bacteriuria (p less than 0.01) and of severe infectious complications (p = 0.004) compared to the controls. Both regimens were equally effective in preventing peri-operative and post-operative acquisition of bacteriuria in patients without bacteriuria at surgery. In patients with bacteriuria before surgery, bacteriuria was found post-operatively in 35% in Group I and in 9% in Group II (p = 0.012), but in 82% of the patients in Group III. Ciprofloxacin inhibited all but 7 of 176 bacterial strains at an MIC of less than or equal to 1 microgram/ml. Given orally, ciprofloxacin is a valuable alternative antimicrobial for use in conjunction with transurethral prostatic resection. A short course is sufficient for prophylaxis, and adequate therapy is achieved with a prolonged regimen. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1104523
- author
- Hellsten, Sverker LU ; Forsgren, Arne LU ; Björk, Thomas LU and Grabe, Magnus LU
- organization
- publishing date
- 1989
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Journal of Infectious Diseases. Supplementum
- volume
- 60
- pages
- 104 - 107
- publisher
- Scandinavian University Press
- external identifiers
-
- pmid:2756349
- scopus:0024308569
- ISSN
- 0300-8878
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Division of Urological Cancers (013243420), Clinical Microbiology, Malmö (013011000), Urology (013243400)
- id
- f75a7e90-c91e-486f-b690-86f6a3f2dfb1 (old id 1104523)
- date added to LUP
- 2016-04-01 16:18:44
- date last changed
- 2021-08-29 03:29:49
@article{f75a7e90-c91e-486f-b690-86f6a3f2dfb1, abstract = {{The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection and compared with that of controls without antibiotic (Group III). Both regimens significantly reduced the frequency of post-operative bacteriuria (p less than 0.01) and of severe infectious complications (p = 0.004) compared to the controls. Both regimens were equally effective in preventing peri-operative and post-operative acquisition of bacteriuria in patients without bacteriuria at surgery. In patients with bacteriuria before surgery, bacteriuria was found post-operatively in 35% in Group I and in 9% in Group II (p = 0.012), but in 82% of the patients in Group III. Ciprofloxacin inhibited all but 7 of 176 bacterial strains at an MIC of less than or equal to 1 microgram/ml. Given orally, ciprofloxacin is a valuable alternative antimicrobial for use in conjunction with transurethral prostatic resection. A short course is sufficient for prophylaxis, and adequate therapy is achieved with a prolonged regimen.}}, author = {{Hellsten, Sverker and Forsgren, Arne and Björk, Thomas and Grabe, Magnus}}, issn = {{0300-8878}}, language = {{eng}}, pages = {{104--107}}, publisher = {{Scandinavian University Press}}, series = {{Scandinavian Journal of Infectious Diseases. Supplementum}}, title = {{Use of ciprofloxacin in patients undergoing transurethral prostatic surgery}}, volume = {{60}}, year = {{1989}}, }