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Recurrent thromboembolism in pregnancy and puerperium. Is there a need for thromboprophylaxis?

Tengborn, Lilian LU ; Bergqvist, D; Mätzsch, Thomas LU ; Bergqvist, A and Hedner, Ulla LU (1989) In American Journal of Obstetrics and Gynecology 160(1). p.90-94
Abstract
By sending a questionnaire (response rate 93%) to 321 women with a history of venous thromboembolism and previous coagulation tests, 72 patients were identified who had a total of 87 pregnancies after the thromboembolic episode. The main aim of the study was to analyze the influence of prophylaxis during pregnancy and delivery on the development of further thromboembolic complications. During pregnancy there was no difference in frequency of thromboses between the group given prophylaxis (n = 20) and the group not receiving it (n = 67). At delivery the frequency of thrombosis was 5.3% among the 57 women given prophylaxis and 11.1% among the 30 without prophylaxis, a difference that is not significant. The implication of these findings is... (More)
By sending a questionnaire (response rate 93%) to 321 women with a history of venous thromboembolism and previous coagulation tests, 72 patients were identified who had a total of 87 pregnancies after the thromboembolic episode. The main aim of the study was to analyze the influence of prophylaxis during pregnancy and delivery on the development of further thromboembolic complications. During pregnancy there was no difference in frequency of thromboses between the group given prophylaxis (n = 20) and the group not receiving it (n = 67). At delivery the frequency of thrombosis was 5.3% among the 57 women given prophylaxis and 11.1% among the 30 without prophylaxis, a difference that is not significant. The implication of these findings is discussed both concerning the indications for giving prophylaxis and concerning the problem of designing relevant prophylactic trials. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
American Journal of Obstetrics and Gynecology
volume
160
issue
1
pages
90 - 94
publisher
Elsevier
external identifiers
  • pmid:2912109
  • scopus:0024496352
ISSN
1097-6868
language
English
LU publication?
yes
id
504d4817-d957-40fb-b8f9-32ccd8a74221 (old id 1104607)
date added to LUP
2008-08-06 11:44:54
date last changed
2017-08-06 03:41:26
@article{504d4817-d957-40fb-b8f9-32ccd8a74221,
  abstract     = {By sending a questionnaire (response rate 93%) to 321 women with a history of venous thromboembolism and previous coagulation tests, 72 patients were identified who had a total of 87 pregnancies after the thromboembolic episode. The main aim of the study was to analyze the influence of prophylaxis during pregnancy and delivery on the development of further thromboembolic complications. During pregnancy there was no difference in frequency of thromboses between the group given prophylaxis (n = 20) and the group not receiving it (n = 67). At delivery the frequency of thrombosis was 5.3% among the 57 women given prophylaxis and 11.1% among the 30 without prophylaxis, a difference that is not significant. The implication of these findings is discussed both concerning the indications for giving prophylaxis and concerning the problem of designing relevant prophylactic trials.},
  author       = {Tengborn, Lilian and Bergqvist, D and Mätzsch, Thomas and Bergqvist, A and Hedner, Ulla},
  issn         = {1097-6868},
  language     = {eng},
  number       = {1},
  pages        = {90--94},
  publisher    = {Elsevier},
  series       = {American Journal of Obstetrics and Gynecology},
  title        = {Recurrent thromboembolism in pregnancy and puerperium. Is there a need for thromboprophylaxis?},
  volume       = {160},
  year         = {1989},
}