Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Assays of the biological activities of guaiane sesquiterpenoids isolated from the fruit bodies of edible lactarius species

Anke, H ; Bergendorff, Ola LU and Sterner, Olov LU (1989) In Food and Chemical Toxicology 27(6). p.393-397
Abstract
Three sesquiterpenoids that are found in the edible mushrooms Lactarius deliciosus, L. deterrimus and L. sanguifluus, have been assayed for biological activity. The compounds tested were a stearic acid ester of a sesquiterpene (I) and a sesquiterpene aldehyde (lactaroviolin, II) and alcohol (deterrol, III). The assays used were for mutagenic activity in the Ames Salmonella assay, for antimicrobial activity against bacterial fungi and algae, for cytotoxicity against Ehrlich ascitic tumour cells and L 1210 cells, and for phytotoxic activity against Lepidium sativum and Seteria italica. All three compounds showed weak mutagenic activity in the Ames assay. Two compounds (II and III) were found to have moderate cytotoxic activity and one (III)... (More)
Three sesquiterpenoids that are found in the edible mushrooms Lactarius deliciosus, L. deterrimus and L. sanguifluus, have been assayed for biological activity. The compounds tested were a stearic acid ester of a sesquiterpene (I) and a sesquiterpene aldehyde (lactaroviolin, II) and alcohol (deterrol, III). The assays used were for mutagenic activity in the Ames Salmonella assay, for antimicrobial activity against bacterial fungi and algae, for cytotoxicity against Ehrlich ascitic tumour cells and L 1210 cells, and for phytotoxic activity against Lepidium sativum and Seteria italica. All three compounds showed weak mutagenic activity in the Ames assay. Two compounds (II and III) were found to have moderate cytotoxic activity and one (III) exhibited weak antibacterial activity. No compound revealed phytotoxic, algicidal or antifungal activity. (Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Food and Chemical Toxicology
volume
27
issue
6
pages
393 - 397
publisher
Elsevier
external identifiers
  • pmid:2792969
  • scopus:0024436412
ISSN
0278-6915
DOI
10.1016/0278-6915(89)90145-2
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)
id
28235210-3a8e-4cff-b20c-4b94569e2aa1 (old id 1104632)
date added to LUP
2016-04-01 17:11:59
date last changed
2021-09-26 05:30:30
@article{28235210-3a8e-4cff-b20c-4b94569e2aa1,
  abstract     = {{Three sesquiterpenoids that are found in the edible mushrooms Lactarius deliciosus, L. deterrimus and L. sanguifluus, have been assayed for biological activity. The compounds tested were a stearic acid ester of a sesquiterpene (I) and a sesquiterpene aldehyde (lactaroviolin, II) and alcohol (deterrol, III). The assays used were for mutagenic activity in the Ames Salmonella assay, for antimicrobial activity against bacterial fungi and algae, for cytotoxicity against Ehrlich ascitic tumour cells and L 1210 cells, and for phytotoxic activity against Lepidium sativum and Seteria italica. All three compounds showed weak mutagenic activity in the Ames assay. Two compounds (II and III) were found to have moderate cytotoxic activity and one (III) exhibited weak antibacterial activity. No compound revealed phytotoxic, algicidal or antifungal activity.}},
  author       = {{Anke, H and Bergendorff, Ola and Sterner, Olov}},
  issn         = {{0278-6915}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{393--397}},
  publisher    = {{Elsevier}},
  series       = {{Food and Chemical Toxicology}},
  title        = {{Assays of the biological activities of guaiane sesquiterpenoids isolated from the fruit bodies of edible lactarius species}},
  url          = {{http://dx.doi.org/10.1016/0278-6915(89)90145-2}},
  doi          = {{10.1016/0278-6915(89)90145-2}},
  volume       = {{27}},
  year         = {{1989}},
}