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Synovial fluid acidosis correlates with radiological joint destruction in rheumatoid arthritis knee joints

Geborek, Pierre LU ; Saxne, Tore LU ; Pettersson, H and Wollheim, Frank LU (1989) In Journal of Rheumatology 16(4). p.468-472
Abstract
Metabolic variables in samples of synovial fluid (SF) from 33 rheumatoid arthritis (RA) knees were analyzed. These variables were correlated with radiological destruction and SF proteoglycan concentrations. SF acidosis correlated with radiological involvement (rs = 0.62, p less than 0.002), but not with proteoglycan concentrations. A weak correlation was found between SF acidosis and granulocyte concentrations (rs = 0.37, 0.02 less than p less than 0.05). Metabolic variables covaried as expected. Samples from right and left knees from the same patients correlated regarding cellular and metabolic variables. Our results indicate insufficient nutritional supply in RA joints with increasing radiological involvement.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Rheumatology
volume
16
issue
4
pages
468 - 472
publisher
J Rheumatol Publ Co
external identifiers
  • pmid:2746586
  • scopus:0024314320
ISSN
0315-162X
language
English
LU publication?
yes
id
740a744b-9410-4d14-bc78-60c4d6f92d7f (old id 1104720)
date added to LUP
2008-08-06 14:03:32
date last changed
2017-01-01 04:47:37
@article{740a744b-9410-4d14-bc78-60c4d6f92d7f,
  abstract     = {Metabolic variables in samples of synovial fluid (SF) from 33 rheumatoid arthritis (RA) knees were analyzed. These variables were correlated with radiological destruction and SF proteoglycan concentrations. SF acidosis correlated with radiological involvement (rs = 0.62, p less than 0.002), but not with proteoglycan concentrations. A weak correlation was found between SF acidosis and granulocyte concentrations (rs = 0.37, 0.02 less than p less than 0.05). Metabolic variables covaried as expected. Samples from right and left knees from the same patients correlated regarding cellular and metabolic variables. Our results indicate insufficient nutritional supply in RA joints with increasing radiological involvement.},
  author       = {Geborek, Pierre and Saxne, Tore and Pettersson, H and Wollheim, Frank},
  issn         = {0315-162X},
  language     = {eng},
  number       = {4},
  pages        = {468--472},
  publisher    = {J Rheumatol Publ Co},
  series       = {Journal of Rheumatology},
  title        = {Synovial fluid acidosis correlates with radiological joint destruction in rheumatoid arthritis knee joints},
  volume       = {16},
  year         = {1989},
}