Synovial fluid acidosis correlates with radiological joint destruction in rheumatoid arthritis knee joints
(1989) In Journal of Rheumatology 16(4). p.468-472- Abstract
- Metabolic variables in samples of synovial fluid (SF) from 33 rheumatoid arthritis (RA) knees were analyzed. These variables were correlated with radiological destruction and SF proteoglycan concentrations. SF acidosis correlated with radiological involvement (rs = 0.62, p less than 0.002), but not with proteoglycan concentrations. A weak correlation was found between SF acidosis and granulocyte concentrations (rs = 0.37, 0.02 less than p less than 0.05). Metabolic variables covaried as expected. Samples from right and left knees from the same patients correlated regarding cellular and metabolic variables. Our results indicate insufficient nutritional supply in RA joints with increasing radiological involvement.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1104720
- author
- Geborek, Pierre LU ; Saxne, Tore LU ; Pettersson, H and Wollheim, Frank LU
- organization
- publishing date
- 1989
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Rheumatology
- volume
- 16
- issue
- 4
- pages
- 468 - 472
- publisher
- Journal of Rheumatology Publishing Company Limited
- external identifiers
-
- pmid:2746586
- scopus:0024314320
- ISSN
- 0315-162X
- language
- English
- LU publication?
- yes
- id
- 740a744b-9410-4d14-bc78-60c4d6f92d7f (old id 1104720)
- date added to LUP
- 2016-04-01 12:03:18
- date last changed
- 2021-08-15 03:32:52
@article{740a744b-9410-4d14-bc78-60c4d6f92d7f, abstract = {{Metabolic variables in samples of synovial fluid (SF) from 33 rheumatoid arthritis (RA) knees were analyzed. These variables were correlated with radiological destruction and SF proteoglycan concentrations. SF acidosis correlated with radiological involvement (rs = 0.62, p less than 0.002), but not with proteoglycan concentrations. A weak correlation was found between SF acidosis and granulocyte concentrations (rs = 0.37, 0.02 less than p less than 0.05). Metabolic variables covaried as expected. Samples from right and left knees from the same patients correlated regarding cellular and metabolic variables. Our results indicate insufficient nutritional supply in RA joints with increasing radiological involvement.}}, author = {{Geborek, Pierre and Saxne, Tore and Pettersson, H and Wollheim, Frank}}, issn = {{0315-162X}}, language = {{eng}}, number = {{4}}, pages = {{468--472}}, publisher = {{Journal of Rheumatology Publishing Company Limited}}, series = {{Journal of Rheumatology}}, title = {{Synovial fluid acidosis correlates with radiological joint destruction in rheumatoid arthritis knee joints}}, volume = {{16}}, year = {{1989}}, }