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Protein kinase C modulation of the ethanol effect on serotonin2 receptor transduction in astrocytes

Simonsson, Per LU ; Hansson, Elisabeth and Alling, Christer LU (1989) In Alcohol and Alcoholism 24(5). p.401-404
Abstract
Acute ethanol exposure stimulated serotonin2 receptor signalling in cultured astrocytes. Pretreatment with the protein kinase C inhibitor H7 significantly increased the ethanol-induced potentiation of [3H]-inositol phosphates accumulation. The increase could be explained by an augmented activation of phospholipase C. The results indicate a role of PKC for the modulation of ethanol effects on cellular signalling.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Alcohol and Alcoholism
volume
24
issue
5
pages
401 - 404
publisher
Oxford University Press
external identifiers
  • pmid:2554934
  • scopus:0024829805
ISSN
1464-3502
language
English
LU publication?
yes
id
ef190104-f624-493e-a3a3-3ac25cf41b4c (old id 1104759)
alternative location
http://alcalc.oxfordjournals.org/cgi/reprint/24/5/401
date added to LUP
2008-08-06 14:37:36
date last changed
2017-01-01 05:11:25
@article{ef190104-f624-493e-a3a3-3ac25cf41b4c,
  abstract     = {Acute ethanol exposure stimulated serotonin2 receptor signalling in cultured astrocytes. Pretreatment with the protein kinase C inhibitor H7 significantly increased the ethanol-induced potentiation of [3H]-inositol phosphates accumulation. The increase could be explained by an augmented activation of phospholipase C. The results indicate a role of PKC for the modulation of ethanol effects on cellular signalling.},
  author       = {Simonsson, Per and Hansson, Elisabeth and Alling, Christer},
  issn         = {1464-3502},
  language     = {eng},
  number       = {5},
  pages        = {401--404},
  publisher    = {Oxford University Press},
  series       = {Alcohol and Alcoholism},
  title        = {Protein kinase C modulation of the ethanol effect on serotonin2 receptor transduction in astrocytes},
  volume       = {24},
  year         = {1989},
}