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Trigeminal fibre collaterals storing substance P and calcitonin gene-related peptide associate with ganglion cells containing choline acetyltransferase and vasoactive intestinal polypeptide in the sphenopalatine ganglion of the rat. An axon reflex modulating parasympathetic ganglionic activity?

Suzuki, N; Hardebo, Jan Erik LU and Owman, Christer LU (1989) In Neuroscience 30(3). p.595-604
Abstract
In immunohistochemical studies on rat two types of nerve fibres, both showing substance P and calcitonin gene-related peptide-like immunoreactivity, have been localized in the sphenopalatine ganglion, the principal cells of which contain both vasoactive intestinal polypeptide and choline acetyltransferase. One fine-calibre fibre type forms basket-like arrangements around approximately 3-5% of the principal neurons, whereas another, more coarse type traverses the ganglion without making contacts with the ganglion cells. By transection of nerves connecting with the ganglion, in combination with retrograde tracing experiments, it was concluded that the fine-calibre fibres exclusively come from the trigeminal ganglion, whereas the second type... (More)
In immunohistochemical studies on rat two types of nerve fibres, both showing substance P and calcitonin gene-related peptide-like immunoreactivity, have been localized in the sphenopalatine ganglion, the principal cells of which contain both vasoactive intestinal polypeptide and choline acetyltransferase. One fine-calibre fibre type forms basket-like arrangements around approximately 3-5% of the principal neurons, whereas another, more coarse type traverses the ganglion without making contacts with the ganglion cells. By transection of nerves connecting with the ganglion, in combination with retrograde tracing experiments, it was concluded that the fine-calibre fibres exclusively come from the trigeminal ganglion, whereas the second type in addition, and mainly, originate in the internal carotid ganglion which is situated along the greater superficial petrosal nerve and the pterygoid nerve at their junction with the internal carotid nerve. The brain vasculature was shown to be one target structure for the innervated principal cells in the sphenopalatine ganglion. The arrangement provides the functional possibility for a modulatory interaction between the autonomic and sensory systems, thus resembling an axon reflex mechanism in the peripheral nervous system. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
vasoactive intestinal polypeptide, VIP, CGRP, calcitonin gene-related peptide, ChAT, choline acetyltransferase, FITC, fluorescein isothiocyanate, GSPN, greater superficial petrosal nerve, PN, pterygoid nerve, SP, substance P, SPG, sphenopalatine ganglion, TB, True Blue, TRITC, tetramethyl rhodamine isothiocyanate
in
Neuroscience
volume
30
issue
3
pages
595 - 604
publisher
Elsevier
external identifiers
  • pmid:2475817
  • scopus:0024348069
ISSN
1873-7544
DOI
10.1016/0306-4522(89)90154-1
language
English
LU publication?
yes
id
5a8513a4-d4d2-4598-a115-ef9c0109e6f5 (old id 1104941)
date added to LUP
2008-08-06 16:23:40
date last changed
2017-11-19 03:34:38
@article{5a8513a4-d4d2-4598-a115-ef9c0109e6f5,
  abstract     = {In immunohistochemical studies on rat two types of nerve fibres, both showing substance P and calcitonin gene-related peptide-like immunoreactivity, have been localized in the sphenopalatine ganglion, the principal cells of which contain both vasoactive intestinal polypeptide and choline acetyltransferase. One fine-calibre fibre type forms basket-like arrangements around approximately 3-5% of the principal neurons, whereas another, more coarse type traverses the ganglion without making contacts with the ganglion cells. By transection of nerves connecting with the ganglion, in combination with retrograde tracing experiments, it was concluded that the fine-calibre fibres exclusively come from the trigeminal ganglion, whereas the second type in addition, and mainly, originate in the internal carotid ganglion which is situated along the greater superficial petrosal nerve and the pterygoid nerve at their junction with the internal carotid nerve. The brain vasculature was shown to be one target structure for the innervated principal cells in the sphenopalatine ganglion. The arrangement provides the functional possibility for a modulatory interaction between the autonomic and sensory systems, thus resembling an axon reflex mechanism in the peripheral nervous system.},
  author       = {Suzuki, N and Hardebo, Jan Erik and Owman, Christer},
  issn         = {1873-7544},
  keyword      = {vasoactive intestinal polypeptide,VIP,CGRP,calcitonin gene-related peptide,ChAT,choline acetyltransferase,FITC,fluorescein isothiocyanate,GSPN,greater superficial petrosal nerve,PN,pterygoid nerve,SP,substance P,SPG,sphenopalatine ganglion,TB,True Blue,TRITC,tetramethyl rhodamine isothiocyanate},
  language     = {eng},
  number       = {3},
  pages        = {595--604},
  publisher    = {Elsevier},
  series       = {Neuroscience},
  title        = {Trigeminal fibre collaterals storing substance P and calcitonin gene-related peptide associate with ganglion cells containing choline acetyltransferase and vasoactive intestinal polypeptide in the sphenopalatine ganglion of the rat. An axon reflex modulating parasympathetic ganglionic activity?},
  url          = {http://dx.doi.org/10.1016/0306-4522(89)90154-1},
  volume       = {30},
  year         = {1989},
}