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Immune response to collagen impregnated Dacron double velour grafts for aortic and aorto-femoral reconstructions

Norgren, Lars LU ; Holtås, Stig LU ; Persson, Gunnar ; Ribbe, Else LU ; Saxne, Tore LU and Thörne, Johan LU (1990) In European Journal of Vascular Surgery 4(4). p.379-384
Abstract
This study presents 20 patients, randomised to receive either a collagen-treated or an ordinary Dacron graft for aortic reconstructions, and the results of a skin-prick test, blood parameters and ELISA for anti-collagen antibodies as well as NMR pictures during a 6 week follow-up period. Forty per cent (4/11) of those receiving a collagen impregnated graft had a significantly increased titre of antibodies and NMR revealed in two out of 11 patients either a slightly increased amount of fluid or fibrosis around the graft, both collagen impregnated. No differences were found between the graft groups concerning body temperature and leucocyte or platelet counts. The skin-prick test for collagen was negative in all cases.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Dacron grafts, Collagen impregnation, Immune response
in
European Journal of Vascular Surgery
volume
4
issue
4
pages
379 - 384
publisher
Elsevier
external identifiers
  • pmid:2144492
  • scopus:0025148934
ISSN
0950-821X
DOI
10.1016/S0950-821X(05)80871-0
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Diagnostic Radiology, (Lund) (013038000), Emergency medicine/Medicine/Surgery (013240200), Department of Rheumatology (013036000), Surgery (Lund) (013009000)
id
5fd6dd90-05cb-4166-94b0-e959abbf723f (old id 1105234)
date added to LUP
2016-04-01 16:11:39
date last changed
2020-01-12 19:07:50
@article{5fd6dd90-05cb-4166-94b0-e959abbf723f,
  abstract     = {This study presents 20 patients, randomised to receive either a collagen-treated or an ordinary Dacron graft for aortic reconstructions, and the results of a skin-prick test, blood parameters and ELISA for anti-collagen antibodies as well as NMR pictures during a 6 week follow-up period. Forty per cent (4/11) of those receiving a collagen impregnated graft had a significantly increased titre of antibodies and NMR revealed in two out of 11 patients either a slightly increased amount of fluid or fibrosis around the graft, both collagen impregnated. No differences were found between the graft groups concerning body temperature and leucocyte or platelet counts. The skin-prick test for collagen was negative in all cases.},
  author       = {Norgren, Lars and Holtås, Stig and Persson, Gunnar and Ribbe, Else and Saxne, Tore and Thörne, Johan},
  issn         = {0950-821X},
  language     = {eng},
  number       = {4},
  pages        = {379--384},
  publisher    = {Elsevier},
  series       = {European Journal of Vascular Surgery},
  title        = {Immune response to collagen impregnated Dacron double velour grafts for aortic and aorto-femoral reconstructions},
  url          = {http://dx.doi.org/10.1016/S0950-821X(05)80871-0},
  doi          = {10.1016/S0950-821X(05)80871-0},
  volume       = {4},
  year         = {1990},
}