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Central origins of preganglionic fibers to the sphenopalatine ganglion in the rat. A fluorescent retrograde tracer study with special reference to its relation to central catecholaminergic systems

Suzuki, Norihiro; Hardebo, Jan Erik LU ; Skagerberg, Gunnar LU and Owman, Christer LU (1990) In Journal of the Autonomic Nervous System 30(2). p.101-109
Abstract
The brainstem origin of preganglionic fibers to the sphenopalatine ganglion in rat was revealed by the aid of the retrograde axonal tracer True Blue (which does not traverse to a second order neuron) applied deep in the sphenopalatine ganglion or the Vidian nerve on one side. The majority of fibers originate in the ipsilateral lacrimo-muconasal nucleus in the ventrolateral rostral medulla oblongata and caudal pons. A smaller number of fibers originate more dorsomedially and caudally in the medullary reticular formation. After application to the ganglion a third small group of labelled neurons was found more rostrally in the brainstem, in the reticular formation ventrolateral to the caudal part of the dorsal raphe nucleus. Simultaneous... (More)
The brainstem origin of preganglionic fibers to the sphenopalatine ganglion in rat was revealed by the aid of the retrograde axonal tracer True Blue (which does not traverse to a second order neuron) applied deep in the sphenopalatine ganglion or the Vidian nerve on one side. The majority of fibers originate in the ipsilateral lacrimo-muconasal nucleus in the ventrolateral rostral medulla oblongata and caudal pons. A smaller number of fibers originate more dorsomedially and caudally in the medullary reticular formation. After application to the ganglion a third small group of labelled neurons was found more rostrally in the brainstem, in the reticular formation ventrolateral to the caudal part of the dorsal raphe nucleus. Simultaneous visualization of catecholaminergic nerves revealed that the labelled neurons in the lacrimo-muconasal nucleus were heavily innervated by catecholaminergic fibers. It appears from previous studies that the preganglionic neurons may not be cholinergic. None of the labelled neurons in the brainstem stained positively for catecholamines. Thus, further studies are required to elucidate the transmitter(s) used in these neurons. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Sphenopalatine ganglion, Facial nerve
in
Journal of the Autonomic Nervous System
volume
30
issue
2
pages
101 - 109
publisher
Elsevier
external identifiers
  • pmid:2370417
  • scopus:0025314411
ISSN
0165-1838
DOI
10.1016/0165-1838(90)90133-4
language
English
LU publication?
yes
id
184baf72-7f8b-41b8-a04b-c085e6ca0b48 (old id 1105336)
date added to LUP
2008-08-05 12:44:40
date last changed
2017-01-01 06:57:27
@article{184baf72-7f8b-41b8-a04b-c085e6ca0b48,
  abstract     = {The brainstem origin of preganglionic fibers to the sphenopalatine ganglion in rat was revealed by the aid of the retrograde axonal tracer True Blue (which does not traverse to a second order neuron) applied deep in the sphenopalatine ganglion or the Vidian nerve on one side. The majority of fibers originate in the ipsilateral lacrimo-muconasal nucleus in the ventrolateral rostral medulla oblongata and caudal pons. A smaller number of fibers originate more dorsomedially and caudally in the medullary reticular formation. After application to the ganglion a third small group of labelled neurons was found more rostrally in the brainstem, in the reticular formation ventrolateral to the caudal part of the dorsal raphe nucleus. Simultaneous visualization of catecholaminergic nerves revealed that the labelled neurons in the lacrimo-muconasal nucleus were heavily innervated by catecholaminergic fibers. It appears from previous studies that the preganglionic neurons may not be cholinergic. None of the labelled neurons in the brainstem stained positively for catecholamines. Thus, further studies are required to elucidate the transmitter(s) used in these neurons.},
  author       = {Suzuki, Norihiro and Hardebo, Jan Erik and Skagerberg, Gunnar and Owman, Christer},
  issn         = {0165-1838},
  keyword      = {Sphenopalatine ganglion,Facial nerve},
  language     = {eng},
  number       = {2},
  pages        = {101--109},
  publisher    = {Elsevier},
  series       = {Journal of the Autonomic Nervous System},
  title        = {Central origins of preganglionic fibers to the sphenopalatine ganglion in the rat. A fluorescent retrograde tracer study with special reference to its relation to central catecholaminergic systems},
  url          = {http://dx.doi.org/10.1016/0165-1838(90)90133-4},
  volume       = {30},
  year         = {1990},
}