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The effect of dextran 40 and Dazmegrel on early platelet deposition onto vascular grafts

Pärsson, Håkan; Norgren, Lars LU ; Ivancev, Krassi LU and Thörne, Johan LU (1990) In Vasa: European Journal of Vascular Medicine 19(3). p.242-246
Abstract
Platelet deposition onto double velour Dacron (n = 14) and double velour Dacron with internal collagen (n = 14) interposition grafts were examined experimentally. The accumulation was assessed by reinfusion of 111In labelled platelets and imaging with a scintillation camera. One group received Dextran-40 intravenously (n = 14) and one group received Dazmegrel (n = 14) intravenously. No graft occlusions were noted. Differences in effects of Dextran-40 and Dazmegrel were not observed. The study indicates a beneficial effect of infused Dextran-40 as well as Dazmegrel. The explanation might be reduced interaction graft wall versus blood-platelets.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Vasa: European Journal of Vascular Medicine
volume
19
issue
3
pages
242 - 246
publisher
Hans Huber
external identifiers
  • pmid:1700560
  • scopus:0025113077
ISSN
0301-1526
language
English
LU publication?
yes
id
3d67c0c3-aca0-437e-8d02-be9cf71961c4 (old id 1105599)
date added to LUP
2008-08-06 08:51:15
date last changed
2017-01-01 05:02:33
@article{3d67c0c3-aca0-437e-8d02-be9cf71961c4,
  abstract     = {Platelet deposition onto double velour Dacron (n = 14) and double velour Dacron with internal collagen (n = 14) interposition grafts were examined experimentally. The accumulation was assessed by reinfusion of 111In labelled platelets and imaging with a scintillation camera. One group received Dextran-40 intravenously (n = 14) and one group received Dazmegrel (n = 14) intravenously. No graft occlusions were noted. Differences in effects of Dextran-40 and Dazmegrel were not observed. The study indicates a beneficial effect of infused Dextran-40 as well as Dazmegrel. The explanation might be reduced interaction graft wall versus blood-platelets.},
  author       = {Pärsson, Håkan and Norgren, Lars and Ivancev, Krassi and Thörne, Johan},
  issn         = {0301-1526},
  language     = {eng},
  number       = {3},
  pages        = {242--246},
  publisher    = {Hans Huber},
  series       = {Vasa: European Journal of Vascular Medicine},
  title        = {The effect of dextran 40 and Dazmegrel on early platelet deposition onto vascular grafts},
  volume       = {19},
  year         = {1990},
}