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The effect of dextran 40 and Dazmegrel on early platelet deposition onto vascular grafts

Pärsson, Håkan ; Norgren, Lars LU ; Ivancev, Krassi LU and Thörne, Johan LU (1990) In Vasa: European Journal of Vascular Medicine 19(3). p.242-246
Abstract
Platelet deposition onto double velour Dacron (n = 14) and double velour Dacron with internal collagen (n = 14) interposition grafts were examined experimentally. The accumulation was assessed by reinfusion of 111In labelled platelets and imaging with a scintillation camera. One group received Dextran-40 intravenously (n = 14) and one group received Dazmegrel (n = 14) intravenously. No graft occlusions were noted. Differences in effects of Dextran-40 and Dazmegrel were not observed. The study indicates a beneficial effect of infused Dextran-40 as well as Dazmegrel. The explanation might be reduced interaction graft wall versus blood-platelets.
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Vasa: European Journal of Vascular Medicine
volume
19
issue
3
pages
242 - 246
publisher
Verlag Hans Huber
external identifiers
  • pmid:1700560
  • scopus:0025113077
ISSN
0301-1526
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200), Surgery (Lund) (013009000), Medical Radiology Unit (013241410)
id
3d67c0c3-aca0-437e-8d02-be9cf71961c4 (old id 1105599)
date added to LUP
2016-04-01 12:19:25
date last changed
2021-01-03 08:06:37
@article{3d67c0c3-aca0-437e-8d02-be9cf71961c4,
  abstract     = {{Platelet deposition onto double velour Dacron (n = 14) and double velour Dacron with internal collagen (n = 14) interposition grafts were examined experimentally. The accumulation was assessed by reinfusion of 111In labelled platelets and imaging with a scintillation camera. One group received Dextran-40 intravenously (n = 14) and one group received Dazmegrel (n = 14) intravenously. No graft occlusions were noted. Differences in effects of Dextran-40 and Dazmegrel were not observed. The study indicates a beneficial effect of infused Dextran-40 as well as Dazmegrel. The explanation might be reduced interaction graft wall versus blood-platelets.}},
  author       = {{Pärsson, Håkan and Norgren, Lars and Ivancev, Krassi and Thörne, Johan}},
  issn         = {{0301-1526}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{242--246}},
  publisher    = {{Verlag Hans Huber}},
  series       = {{Vasa: European Journal of Vascular Medicine}},
  title        = {{The effect of dextran 40 and Dazmegrel on early platelet deposition onto vascular grafts}},
  volume       = {{19}},
  year         = {{1990}},
}