Life-course perspective on socioeconomic differences in carotid atherosclerosis.
(2002) In Arteriosclerosis, Thrombosis and Vascular Biology 22(10). p.1704-1711- Abstract
- OBJECTIVE: Socioeconomic status (SES) in adulthood is known to be related to carotid atherosclerosis. However, few studies have tried to assess its association with SES from a life-course perspective. METHODS AND RESULTS: We examined the relationship between SES in childhood and in adulthood and carotid atherosclerosis in a general population of Swedish men and women. Carotid stenosis was determined by B-mode ultrasound. Results showed that women whose fathers' occupations involved unskilled manual labor had higher odds of carotid stenosis than did women whose fathers' occupations involved high- or medium-level nonmanual labor, even after adjustment for adult occupational status and risk factors (odds ratio 1.8, 95% CI 1.1 to 2.8). No such... (More)
- OBJECTIVE: Socioeconomic status (SES) in adulthood is known to be related to carotid atherosclerosis. However, few studies have tried to assess its association with SES from a life-course perspective. METHODS AND RESULTS: We examined the relationship between SES in childhood and in adulthood and carotid atherosclerosis in a general population of Swedish men and women. Carotid stenosis was determined by B-mode ultrasound. Results showed that women whose fathers' occupations involved unskilled manual labor had higher odds of carotid stenosis than did women whose fathers' occupations involved high- or medium-level nonmanual labor, even after adjustment for adult occupational status and risk factors (odds ratio 1.8, 95% CI 1.1 to 2.8). No such association appeared in men. Furthermore, the impact of life-course SES on atherosclerosis was examined by using an additive measure of one's combined SES during childhood and adulthood. Among women, the odds of carotid stenosis increased with a rise in exposure to low SES during the life-course (P for trend <0.001). In men, no such trend was found. CONCLUSIONS: The results indicate that the total life-course exposure to low SES, with contributions from childhood and adulthood, seems to play a role in atherogenesis in women. Such a pattern of association could not be shown in men. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/110675
- author
- Rosvall, Maria LU ; Östergren, Per-Olof LU ; Hedblad, Bo LU ; Isacsson, Sven-Olof LU ; Janzon, Lars LU and Berglund, Göran LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- atherosclerosis, carotid arteries, life-course, socioeconomic status
- in
- Arteriosclerosis, Thrombosis and Vascular Biology
- volume
- 22
- issue
- 10
- pages
- 1704 - 1711
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000178686700033
- pmid:12377753
- scopus:0036792641
- ISSN
- 1524-4636
- DOI
- 10.1161/01.ATV.0000032006.75577.24
- language
- English
- LU publication?
- yes
- id
- d302bd02-a0cb-42be-a6af-5fe679cb08c4 (old id 110675)
- date added to LUP
- 2016-04-01 11:48:23
- date last changed
- 2022-01-26 18:30:13
@article{d302bd02-a0cb-42be-a6af-5fe679cb08c4, abstract = {{OBJECTIVE: Socioeconomic status (SES) in adulthood is known to be related to carotid atherosclerosis. However, few studies have tried to assess its association with SES from a life-course perspective. METHODS AND RESULTS: We examined the relationship between SES in childhood and in adulthood and carotid atherosclerosis in a general population of Swedish men and women. Carotid stenosis was determined by B-mode ultrasound. Results showed that women whose fathers' occupations involved unskilled manual labor had higher odds of carotid stenosis than did women whose fathers' occupations involved high- or medium-level nonmanual labor, even after adjustment for adult occupational status and risk factors (odds ratio 1.8, 95% CI 1.1 to 2.8). No such association appeared in men. Furthermore, the impact of life-course SES on atherosclerosis was examined by using an additive measure of one's combined SES during childhood and adulthood. Among women, the odds of carotid stenosis increased with a rise in exposure to low SES during the life-course (P for trend <0.001). In men, no such trend was found. CONCLUSIONS: The results indicate that the total life-course exposure to low SES, with contributions from childhood and adulthood, seems to play a role in atherogenesis in women. Such a pattern of association could not be shown in men.}}, author = {{Rosvall, Maria and Östergren, Per-Olof and Hedblad, Bo and Isacsson, Sven-Olof and Janzon, Lars and Berglund, Göran}}, issn = {{1524-4636}}, keywords = {{atherosclerosis; carotid arteries; life-course; socioeconomic status}}, language = {{eng}}, number = {{10}}, pages = {{1704--1711}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{Arteriosclerosis, Thrombosis and Vascular Biology}}, title = {{Life-course perspective on socioeconomic differences in carotid atherosclerosis.}}, url = {{http://dx.doi.org/10.1161/01.ATV.0000032006.75577.24}}, doi = {{10.1161/01.ATV.0000032006.75577.24}}, volume = {{22}}, year = {{2002}}, }