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Adaptation of signal transduction in brain

Alling, Christer LU ; Gustavsson, L ; Larsson, Christer LU ; Lundqvist, C ; Rodriguez, D and Simonsson, Per LU (1994) In EXS 71. p.19-28
Abstract
Cell culture models were used to study the effects of long-term ethanol exposure on neuronal cells. Effects on phospholipase C and phospholipase D mediated signal transduction were investigated by assaying receptor-binding, G protein function, activities of lipases, formation of second messengers and c-fos mRNA. The signal transduction cascades displayed abnormal activities from 2 to 7 days of exposure which differed from the acute effects. Phosphatidylethanol formed by phospholipase D is an abnormal lipid that may harmfully affect nerve cell function.
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
EXS
volume
71
pages
19 - 28
publisher
Birkhäuser Verlag
external identifiers
  • pmid:8032150
  • scopus:0028248606
ISSN
1023-294X
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Tumour Cell Biology (013017530), Clinical Chemistry, Malmö (013016000)
id
f99e4e56-02d6-45bf-8c1c-97925c6f1cb3 (old id 1107722)
date added to LUP
2016-04-01 16:19:57
date last changed
2020-01-12 19:16:07
@article{f99e4e56-02d6-45bf-8c1c-97925c6f1cb3,
  abstract     = {Cell culture models were used to study the effects of long-term ethanol exposure on neuronal cells. Effects on phospholipase C and phospholipase D mediated signal transduction were investigated by assaying receptor-binding, G protein function, activities of lipases, formation of second messengers and c-fos mRNA. The signal transduction cascades displayed abnormal activities from 2 to 7 days of exposure which differed from the acute effects. Phosphatidylethanol formed by phospholipase D is an abnormal lipid that may harmfully affect nerve cell function.},
  author       = {Alling, Christer and Gustavsson, L and Larsson, Christer and Lundqvist, C and Rodriguez, D and Simonsson, Per},
  issn         = {1023-294X},
  language     = {eng},
  pages        = {19--28},
  publisher    = {Birkhäuser Verlag},
  series       = {EXS},
  title        = {Adaptation of signal transduction in brain},
  volume       = {71},
  year         = {1994},
}