Sephadex-induced granulomatous alveolitis in rat: effects of antigen manipulation
(1994) In American Journal of Industrial Medicine 25(1). p.73-78- Abstract
- A granulomatous alveolitis, with multinuclear cell formation combined with an eosinophilic peribronchiolitis, was achieved in rats by intratracheal administration of sephadex beads (G-200, Pharmacia, Sweden). The pattern of inflammation and the degree of postgranulomatous fibrosis were substantially dampened when the particles were dispersed by ultrasonification. The animals were analyzed with bronchoalveolar lavage and tissue morphology.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1107836
- author
- Bjermer, Leif LU ; Sandstrom, Thomas ; Särnstrand, Bengt LU and Brattsand, Ralph
- publishing date
- 1994
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- bronchoalveolar lavage, allergic alveolitis, eosinophils, lymphocytes, sephadex, organic dusts
- in
- American Journal of Industrial Medicine
- volume
- 25
- issue
- 1
- pages
- 73 - 78
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:7509565
- scopus:0028012689
- ISSN
- 0271-3586
- DOI
- 10.1002/ajim.4700250119
- language
- English
- LU publication?
- no
- id
- ba21a814-ffa1-4c1f-89d4-0d4e328dbf4d (old id 1107836)
- date added to LUP
- 2016-04-01 11:38:33
- date last changed
- 2021-01-03 08:14:15
@article{ba21a814-ffa1-4c1f-89d4-0d4e328dbf4d, abstract = {{A granulomatous alveolitis, with multinuclear cell formation combined with an eosinophilic peribronchiolitis, was achieved in rats by intratracheal administration of sephadex beads (G-200, Pharmacia, Sweden). The pattern of inflammation and the degree of postgranulomatous fibrosis were substantially dampened when the particles were dispersed by ultrasonification. The animals were analyzed with bronchoalveolar lavage and tissue morphology.}}, author = {{Bjermer, Leif and Sandstrom, Thomas and Särnstrand, Bengt and Brattsand, Ralph}}, issn = {{0271-3586}}, keywords = {{bronchoalveolar lavage; allergic alveolitis; eosinophils; lymphocytes; sephadex; organic dusts}}, language = {{eng}}, number = {{1}}, pages = {{73--78}}, publisher = {{John Wiley & Sons Inc.}}, series = {{American Journal of Industrial Medicine}}, title = {{Sephadex-induced granulomatous alveolitis in rat: effects of antigen manipulation}}, url = {{http://dx.doi.org/10.1002/ajim.4700250119}}, doi = {{10.1002/ajim.4700250119}}, volume = {{25}}, year = {{1994}}, }