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Prenylated isoflavanone from the roots of Erythrina sigmoidea

Nkengfack, Augustin E ; Vouffo, Timothee W ; Fomum, Z T ; Meyer, Michele ; Bergendorff, Ola LU and Sterner, Olov LU (1994) In Phytochemistry 36(4). p.1047-1051
Abstract
A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Erythrina sigmoidea, Leguminosae, roots, sigmoidin I, neobavaisoflavone, corylin, phaseollidin, antifungal activity
in
Phytochemistry
volume
36
issue
4
pages
1047 - 1051
publisher
Elsevier
external identifiers
  • pmid:7765206
  • scopus:0028468590
ISSN
0031-9422
DOI
10.1016/S0031-9422(00)90489-8
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240), Department of Dermatology and Venereology (Lund) (013006000)
id
41022e30-c94c-42e1-8e49-1fd6ec902a9f (old id 1108273)
date added to LUP
2016-04-01 16:58:28
date last changed
2020-11-15 05:38:59
@article{41022e30-c94c-42e1-8e49-1fd6ec902a9f,
  abstract     = {A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.},
  author       = {Nkengfack, Augustin E and Vouffo, Timothee W and Fomum, Z T and Meyer, Michele and Bergendorff, Ola and Sterner, Olov},
  issn         = {0031-9422},
  language     = {eng},
  number       = {4},
  pages        = {1047--1051},
  publisher    = {Elsevier},
  series       = {Phytochemistry},
  title        = {Prenylated isoflavanone from the roots of Erythrina sigmoidea},
  url          = {http://dx.doi.org/10.1016/S0031-9422(00)90489-8},
  doi          = {10.1016/S0031-9422(00)90489-8},
  volume       = {36},
  year         = {1994},
}