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Prenylated isoflavanone from the roots of Erythrina sigmoidea

Nkengfack, Augustin E; Vouffo, Timothee W; Fomum, Z T; Meyer, Michele; Bergendorff, Ola LU and Sterner, Olov LU (1994) In Phytochemistry 36(4). p.1047-1051
Abstract
A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Erythrina sigmoidea, Leguminosae, roots, sigmoidin I, neobavaisoflavone, corylin, phaseollidin, antifungal activity
in
Phytochemistry
volume
36
issue
4
pages
1047 - 1051
publisher
Elsevier
external identifiers
  • pmid:7765206
  • scopus:0028468590
ISSN
0031-9422
DOI
10.1016/S0031-9422(00)90489-8
language
English
LU publication?
yes
id
41022e30-c94c-42e1-8e49-1fd6ec902a9f (old id 1108273)
date added to LUP
2008-07-23 16:32:56
date last changed
2017-07-30 04:43:31
@article{41022e30-c94c-42e1-8e49-1fd6ec902a9f,
  abstract     = {A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.},
  author       = {Nkengfack, Augustin E and Vouffo, Timothee W and Fomum, Z T and Meyer, Michele and Bergendorff, Ola and Sterner, Olov},
  issn         = {0031-9422},
  keyword      = {Erythrina sigmoidea,Leguminosae,roots,sigmoidin I,neobavaisoflavone,corylin,phaseollidin,antifungal activity},
  language     = {eng},
  number       = {4},
  pages        = {1047--1051},
  publisher    = {Elsevier},
  series       = {Phytochemistry},
  title        = {Prenylated isoflavanone from the roots of Erythrina sigmoidea},
  url          = {http://dx.doi.org/10.1016/S0031-9422(00)90489-8},
  volume       = {36},
  year         = {1994},
}