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Expression of the Arp protein, a member of the M protein family, is not sufficient to inhibit phagocytosis of Streptococcus pyogenes

Husmann, Linda K; Scott, June R; Lindahl, Gunnar LU and Stenberg, Lars LU (1995) In Infection and Immunity 63(1). p.345-348
Abstract
Many Streptococcus pyogenes immunoglobulin-binding proteins have structural similarities to the antiphagocytic M protein, including the well-known C repeats. One of these molecules is the immunoglobulin A-binding protein Arp, which is expressed by a serotype 4 strain for which no antiphagocytic M protein has yet been described. We expressed Arp4 in an S. pyogenes strain from which the structural gene for the M protein has been deleted and found that Arp4 is not sufficient to inhibit phagocytosis.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Infection and Immunity
volume
63
issue
1
pages
345 - 348
publisher
American Society for Microbiology
external identifiers
  • pmid:7806375
  • scopus:0028855515
ISSN
1098-5522
language
English
LU publication?
yes
id
a900b6a1-6703-4cf5-b66c-0e4a3b8d9b9d (old id 1109102)
alternative location
http://iai.highwire.org/cgi/reprint/63/1/345
date added to LUP
2008-07-25 13:55:13
date last changed
2017-01-15 03:26:35
@article{a900b6a1-6703-4cf5-b66c-0e4a3b8d9b9d,
  abstract     = {Many Streptococcus pyogenes immunoglobulin-binding proteins have structural similarities to the antiphagocytic M protein, including the well-known C repeats. One of these molecules is the immunoglobulin A-binding protein Arp, which is expressed by a serotype 4 strain for which no antiphagocytic M protein has yet been described. We expressed Arp4 in an S. pyogenes strain from which the structural gene for the M protein has been deleted and found that Arp4 is not sufficient to inhibit phagocytosis.},
  author       = {Husmann, Linda K and Scott, June R and Lindahl, Gunnar and Stenberg, Lars},
  issn         = {1098-5522},
  language     = {eng},
  number       = {1},
  pages        = {345--348},
  publisher    = {American Society for Microbiology},
  series       = {Infection and Immunity},
  title        = {Expression of the Arp protein, a member of the M protein family, is not sufficient to inhibit phagocytosis of Streptococcus pyogenes},
  volume       = {63},
  year         = {1995},
}