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Indicators of bone formation in weight lifters

Karlsson, M K; Vergnaud, P; Delmas, P D and Obrant, Karl LU (1995) In Calcified Tissue International 56(3). p.177-180
Abstract
Physical activity has been suggested to be one of the determinants of bone turnover and to prevent age-related bone loss. To examine this we measured the serum levels of osteocalcin (bone Gla-protein, BGP), C-terminal procollagen peptide (PICP), serum alkaline phosphatase, bone-specific alkaline phosphatase, and S-calcium as indices of bone formation in 19 actively performing and 15 ex-lifters. All were nationally or internationally ranked male athletes. Their values were compared with those from 38 age- and gender-matched controls. Actively performing weight lifters had 35% higher (P < 0.05) serum concentration of osteocalcin than the controls. The ex-lifters did not differ from the age-matched controls. Also serum calcium was elevated... (More)
Physical activity has been suggested to be one of the determinants of bone turnover and to prevent age-related bone loss. To examine this we measured the serum levels of osteocalcin (bone Gla-protein, BGP), C-terminal procollagen peptide (PICP), serum alkaline phosphatase, bone-specific alkaline phosphatase, and S-calcium as indices of bone formation in 19 actively performing and 15 ex-lifters. All were nationally or internationally ranked male athletes. Their values were compared with those from 38 age- and gender-matched controls. Actively performing weight lifters had 35% higher (P < 0.05) serum concentration of osteocalcin than the controls. The ex-lifters did not differ from the age-matched controls. Also serum calcium was elevated in active lifters (6%) (P < 0.01) but not in ex-lifters. No difference was found for serum-ALP, B-ALP, or PICP in either of the groups. Our study indicates that in addition to an already documented and well-known higher bone mineral density in heavily exercising athletes, they have an indication of higher bone formation as measured by biochemical markers. In athletes who have retired from competitional training, however, the bone formation does not differ from that of more sedentary controls. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Osteocalcin, Weight lifters, Bone turnover, Athletes
in
Calcified Tissue International
volume
56
issue
3
pages
177 - 180
publisher
Springer
external identifiers
  • pmid:7750019
  • scopus:0028903852
ISSN
1432-0827
DOI
10.1007/BF00298605
language
English
LU publication?
yes
id
0fe4b1fb-95c4-4278-b557-9042f3123f9c (old id 1109242)
date added to LUP
2008-07-25 16:33:57
date last changed
2017-08-20 04:32:47
@article{0fe4b1fb-95c4-4278-b557-9042f3123f9c,
  abstract     = {Physical activity has been suggested to be one of the determinants of bone turnover and to prevent age-related bone loss. To examine this we measured the serum levels of osteocalcin (bone Gla-protein, BGP), C-terminal procollagen peptide (PICP), serum alkaline phosphatase, bone-specific alkaline phosphatase, and S-calcium as indices of bone formation in 19 actively performing and 15 ex-lifters. All were nationally or internationally ranked male athletes. Their values were compared with those from 38 age- and gender-matched controls. Actively performing weight lifters had 35% higher (P &lt; 0.05) serum concentration of osteocalcin than the controls. The ex-lifters did not differ from the age-matched controls. Also serum calcium was elevated in active lifters (6%) (P &lt; 0.01) but not in ex-lifters. No difference was found for serum-ALP, B-ALP, or PICP in either of the groups. Our study indicates that in addition to an already documented and well-known higher bone mineral density in heavily exercising athletes, they have an indication of higher bone formation as measured by biochemical markers. In athletes who have retired from competitional training, however, the bone formation does not differ from that of more sedentary controls.},
  author       = {Karlsson, M K and Vergnaud, P and Delmas, P D and Obrant, Karl},
  issn         = {1432-0827},
  keyword      = {Osteocalcin,Weight lifters,Bone turnover,Athletes},
  language     = {eng},
  number       = {3},
  pages        = {177--180},
  publisher    = {Springer},
  series       = {Calcified Tissue International},
  title        = {Indicators of bone formation in weight lifters},
  url          = {http://dx.doi.org/10.1007/BF00298605},
  volume       = {56},
  year         = {1995},
}