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Spasmolytic flavonols from Artemisia abrotanum

Bergendorff, Ola LU and Sterner, Olov LU (1995) In Planta Medica 61(4). p.370-371
Abstract
Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC50 values for compounds 1-3 are 20-30 mumol/l while compound 4 is less active.
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Planta Medica
volume
61
issue
4
pages
370 - 371
publisher
Georg Thieme Verlag KG
external identifiers
  • pmid:7480189
  • scopus:0029160539
ISSN
0032-0943
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240), Department of Dermatology and Venereology (Lund) (013006000)
id
e86e8604-8f0e-4044-8a4e-4e34ddf288c9 (old id 1109352)
date added to LUP
2016-04-01 11:54:20
date last changed
2020-06-07 03:51:07
@article{e86e8604-8f0e-4044-8a4e-4e34ddf288c9,
  abstract     = {Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC50 values for compounds 1-3 are 20-30 mumol/l while compound 4 is less active.},
  author       = {Bergendorff, Ola and Sterner, Olov},
  issn         = {0032-0943},
  language     = {eng},
  number       = {4},
  pages        = {370--371},
  publisher    = {Georg Thieme Verlag KG},
  series       = {Planta Medica},
  title        = {Spasmolytic flavonols from Artemisia abrotanum},
  volume       = {61},
  year         = {1995},
}