Reovirus type 1 associated with meningitis
(1996) In Scandinavian Journal of Infectious Diseases 28(2). p.117-120- Abstract
- A previously healthy 3-month-old girl presented with symptoms of meningitis, diarrhoea, vomiting and fever. Green monkey kidney (GMK) cells inoculated with cerebrospinal fluid (CSF) revealed reovirus-like particles by electron microscopy. RNA-gel electrophoresis, immunofluorescence and virus neutralization identified the pathogen isolated from CSF as reovirus type 1. Antibody determination by immunofluorescence of paired sera showed a significant antibody titre rise to the CSF isolate and neutralization test revealed a greater than 4-fold antibody titre rise to the CSF isolate. The CSF isolate was also neutralized by reovirus type 1 antibodies. This report represents one of a few associating reovirus with CNS symptoms in humans.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1110216
- author
- Johansson, Hugo LU ; Sveger, Tomas LU ; Ahlfors, Karin ; Ekstrand, Jarl and Svensson, Lennart
- organization
- publishing date
- 1996
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Journal of Infectious Diseases
- volume
- 28
- issue
- 2
- pages
- 117 - 120
- publisher
- Informa Healthcare
- external identifiers
-
- pmid:8792475
- scopus:0030001319
- ISSN
- 1651-1980
- DOI
- 10.3109/00365549609049060
- language
- English
- LU publication?
- yes
- id
- c5624b62-7e1b-4573-9008-80abf1c26859 (old id 1110216)
- date added to LUP
- 2016-04-01 16:31:49
- date last changed
- 2022-01-28 20:23:09
@article{c5624b62-7e1b-4573-9008-80abf1c26859, abstract = {{A previously healthy 3-month-old girl presented with symptoms of meningitis, diarrhoea, vomiting and fever. Green monkey kidney (GMK) cells inoculated with cerebrospinal fluid (CSF) revealed reovirus-like particles by electron microscopy. RNA-gel electrophoresis, immunofluorescence and virus neutralization identified the pathogen isolated from CSF as reovirus type 1. Antibody determination by immunofluorescence of paired sera showed a significant antibody titre rise to the CSF isolate and neutralization test revealed a greater than 4-fold antibody titre rise to the CSF isolate. The CSF isolate was also neutralized by reovirus type 1 antibodies. This report represents one of a few associating reovirus with CNS symptoms in humans.}}, author = {{Johansson, Hugo and Sveger, Tomas and Ahlfors, Karin and Ekstrand, Jarl and Svensson, Lennart}}, issn = {{1651-1980}}, language = {{eng}}, number = {{2}}, pages = {{117--120}}, publisher = {{Informa Healthcare}}, series = {{Scandinavian Journal of Infectious Diseases}}, title = {{Reovirus type 1 associated with meningitis}}, url = {{http://dx.doi.org/10.3109/00365549609049060}}, doi = {{10.3109/00365549609049060}}, volume = {{28}}, year = {{1996}}, }