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Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions

Björkman-Burtscher, Isabella LU ; Ståhlberg, Freddy LU and Holtås, Stig LU (1997) In Acta Radiologica 38(6). p.953-960
Abstract
PURPOSE: To describe the introduction and performance of proton MR spectroscopy (1H-MRS) in the daily routine of a modern standard MR unit. MATERIAL AND METHODS: Over an 8-month period, 52 patients with brain lesions were studied with 1H-MRS, using SE and STEAM sequences for chemical-shift imaging and single-volume spectroscopy. The quality of the spectra was graded from 1 (best) to 3, and the main factors influencing the quality of the spectra were evaluated. RESULTS: Of the measurements: 85% were graded as 1; 12% as 2; and 3% as 3. The main reasons for poor spectral quality were: the unfortunate positioning of the VOI; hemorrhage; and/or postoperative changes within the VOI. Of 40 patients with a final diagnosis: MRS provided an... (More)
PURPOSE: To describe the introduction and performance of proton MR spectroscopy (1H-MRS) in the daily routine of a modern standard MR unit. MATERIAL AND METHODS: Over an 8-month period, 52 patients with brain lesions were studied with 1H-MRS, using SE and STEAM sequences for chemical-shift imaging and single-volume spectroscopy. The quality of the spectra was graded from 1 (best) to 3, and the main factors influencing the quality of the spectra were evaluated. RESULTS: Of the measurements: 85% were graded as 1; 12% as 2; and 3% as 3. The main reasons for poor spectral quality were: the unfortunate positioning of the VOI; hemorrhage; and/or postoperative changes within the VOI. Of 40 patients with a final diagnosis: MRS provided an increased confidence in MR diagnosis in 18 cases; MRS contributed significantly to preoperative diagnosis in 3 cases; and the spectra were not specific (n = 10) or were difficult to evaluate (n = 9) owing to reduced quality (grade 2 or 3) in 19 cases. CONCLUSION: MRS of the brain can provide a high percentage of interpretable spectra and frequently can increase confidence in the MR diagnosis of brain lesions in clinical routine. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Radiologica
volume
38
issue
6
pages
953 - 960
publisher
John Wiley & Sons
external identifiers
  • pmid:9394648
  • scopus:0031278360
ISSN
1600-0455
language
English
LU publication?
yes
id
a7936a38-f4f0-40ce-97d4-68f75a808034 (old id 1111623)
date added to LUP
2008-07-18 09:28:19
date last changed
2017-01-01 06:55:02
@article{a7936a38-f4f0-40ce-97d4-68f75a808034,
  abstract     = {PURPOSE: To describe the introduction and performance of proton MR spectroscopy (1H-MRS) in the daily routine of a modern standard MR unit. MATERIAL AND METHODS: Over an 8-month period, 52 patients with brain lesions were studied with 1H-MRS, using SE and STEAM sequences for chemical-shift imaging and single-volume spectroscopy. The quality of the spectra was graded from 1 (best) to 3, and the main factors influencing the quality of the spectra were evaluated. RESULTS: Of the measurements: 85% were graded as 1; 12% as 2; and 3% as 3. The main reasons for poor spectral quality were: the unfortunate positioning of the VOI; hemorrhage; and/or postoperative changes within the VOI. Of 40 patients with a final diagnosis: MRS provided an increased confidence in MR diagnosis in 18 cases; MRS contributed significantly to preoperative diagnosis in 3 cases; and the spectra were not specific (n = 10) or were difficult to evaluate (n = 9) owing to reduced quality (grade 2 or 3) in 19 cases. CONCLUSION: MRS of the brain can provide a high percentage of interpretable spectra and frequently can increase confidence in the MR diagnosis of brain lesions in clinical routine.},
  author       = {Björkman-Burtscher, Isabella and Ståhlberg, Freddy and Holtås, Stig},
  issn         = {1600-0455},
  language     = {eng},
  number       = {6},
  pages        = {953--960},
  publisher    = {John Wiley & Sons},
  series       = {Acta Radiologica},
  title        = {Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions},
  volume       = {38},
  year         = {1997},
}