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An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport

Belitsky, B R; Gustafsson, Mattias LU ; Sonenshein, A L and von Wachenfeldt, Claes LU (1997) In Journal of Bacteriology 179(17). p.5448-5457
Abstract
The azlB locus of Bacillus subtilis was defined previously by a mutation conferring resistance to a leucine analog, 4-azaleucine (J. B. Ward, Jr., and S. A. Zahler, J. Bacteriol. 116:727-735, 1973). In this report, azlB is shown to be the first gene of an operon apparently involved in branched-chain amino acid transport. The product of the azlB gene is an Lrp-like protein that negatively regulates expression of the azlBCDEF operon. Resistance to 4-azaleucine in azlB mutants is due to overproduction of AzlC and AzlD, two novel hydrophobic proteins.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Bacteriology
volume
179
issue
17
pages
5448 - 5457
publisher
American Society for Microbiology
external identifiers
  • pmid:9287000
  • scopus:0030885438
ISSN
0021-9193
language
English
LU publication?
yes
id
4e41ad28-a68a-44c9-88fe-3468160150e0 (old id 1111908)
alternative location
http://www.pubmedcentral.nih.gov/articlerender.fcgi?rendertype=abstract&artid=179416
date added to LUP
2008-07-21 09:38:46
date last changed
2017-09-03 03:38:35
@article{4e41ad28-a68a-44c9-88fe-3468160150e0,
  abstract     = {The azlB locus of Bacillus subtilis was defined previously by a mutation conferring resistance to a leucine analog, 4-azaleucine (J. B. Ward, Jr., and S. A. Zahler, J. Bacteriol. 116:727-735, 1973). In this report, azlB is shown to be the first gene of an operon apparently involved in branched-chain amino acid transport. The product of the azlB gene is an Lrp-like protein that negatively regulates expression of the azlBCDEF operon. Resistance to 4-azaleucine in azlB mutants is due to overproduction of AzlC and AzlD, two novel hydrophobic proteins.},
  author       = {Belitsky, B R and Gustafsson, Mattias and Sonenshein, A L and von Wachenfeldt, Claes},
  issn         = {0021-9193},
  language     = {eng},
  number       = {17},
  pages        = {5448--5457},
  publisher    = {American Society for Microbiology},
  series       = {Journal of Bacteriology},
  title        = {An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport},
  volume       = {179},
  year         = {1997},
}