An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport
(1997) In Journal of Bacteriology 179(17). p.5448-5457- Abstract
- The azlB locus of Bacillus subtilis was defined previously by a mutation conferring resistance to a leucine analog, 4-azaleucine (J. B. Ward, Jr., and S. A. Zahler, J. Bacteriol. 116:727-735, 1973). In this report, azlB is shown to be the first gene of an operon apparently involved in branched-chain amino acid transport. The product of the azlB gene is an Lrp-like protein that negatively regulates expression of the azlBCDEF operon. Resistance to 4-azaleucine in azlB mutants is due to overproduction of AzlC and AzlD, two novel hydrophobic proteins.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1111908
- author
- Belitsky, B R ; Gustafsson, Mattias LU ; Sonenshein, A L and von Wachenfeldt, Claes LU
- organization
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Bacteriology
- volume
- 179
- issue
- 17
- pages
- 5448 - 5457
- publisher
- American Society for Microbiology
- external identifiers
-
- pmid:9287000
- scopus:0030885438
- ISSN
- 0021-9193
- language
- English
- LU publication?
- yes
- id
- 4e41ad28-a68a-44c9-88fe-3468160150e0 (old id 1111908)
- alternative location
- http://www.pubmedcentral.nih.gov/articlerender.fcgi?rendertype=abstract&artid=179416
- date added to LUP
- 2016-04-01 11:42:57
- date last changed
- 2021-01-28 03:22:46
@article{4e41ad28-a68a-44c9-88fe-3468160150e0, abstract = {The azlB locus of Bacillus subtilis was defined previously by a mutation conferring resistance to a leucine analog, 4-azaleucine (J. B. Ward, Jr., and S. A. Zahler, J. Bacteriol. 116:727-735, 1973). In this report, azlB is shown to be the first gene of an operon apparently involved in branched-chain amino acid transport. The product of the azlB gene is an Lrp-like protein that negatively regulates expression of the azlBCDEF operon. Resistance to 4-azaleucine in azlB mutants is due to overproduction of AzlC and AzlD, two novel hydrophobic proteins.}, author = {Belitsky, B R and Gustafsson, Mattias and Sonenshein, A L and von Wachenfeldt, Claes}, issn = {0021-9193}, language = {eng}, number = {17}, pages = {5448--5457}, publisher = {American Society for Microbiology}, series = {Journal of Bacteriology}, title = {An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport}, url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?rendertype=abstract&artid=179416}, volume = {179}, year = {1997}, }