Minor components with smooth muscle relaxing properties from scented myrrh (Commiphora guidotti)
Andersson, Maria ; Bergendorff, Ola LU ; Shan, Rudong ; Zygmunt, Peter LU
and Sterner, Olov
LU
(1997)
In Planta Medica
63(3).
p.251-254
- Abstract
- All sesquiterpenes present in a sample of scented myrrh were isolated and characterised. Seven compounds, with cadinane, guaiane, oplopane, and eudesmane skeletons, were obtained, of which two are new and two are reported from a natural source for the first time. The major component, T-cadinol, has previously been shown to possess smooth muscle-relaxing properties, and the major purpose of the investigation was to compare the effects of the minor and more polar sesquiterpenes with that of T-cadinol in the rat aorta. Like T-cadinol, the minor sesquiterpenes are more efficient in reducing K(+)-induced contractions than those induced by the alpha-adrenoceptor agonist phenylephrine, however, they were all less potent than T-cadinol.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1111941
- author
- Andersson, Maria
; Bergendorff, Ola
LU
; Shan, Rudong
; Zygmunt, Peter
LU
and Sterner, Olov
LU
- organization
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Scented myrrh, Commiphora guidotti, Burseraceae, sesquiterpenes, T-cadinol, smooth muscle relaxant
- in
- Planta Medica
- volume
- 63
- issue
- 3
- pages
- 251 - 254
- publisher
- Georg Thieme Verlag
- external identifiers
-
- pmid:9225607
- scopus:0031157055
- ISSN
- 0032-0943
- DOI
- 10.1055/s-2006-957665
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Division of Clinical Chemistry and Pharmacology (013250300), Organic chemistry (S/LTH) (011001240)
- id
- 1723c7ce-7253-413c-b6b4-3a6357db1ad4 (old id 1111941)
- date added to LUP
- 2016-04-01 12:19:25
- date last changed
- 2022-04-13 17:28:00
@article{1723c7ce-7253-413c-b6b4-3a6357db1ad4,
abstract = {{All sesquiterpenes present in a sample of scented myrrh were isolated and characterised. Seven compounds, with cadinane, guaiane, oplopane, and eudesmane skeletons, were obtained, of which two are new and two are reported from a natural source for the first time. The major component, T-cadinol, has previously been shown to possess smooth muscle-relaxing properties, and the major purpose of the investigation was to compare the effects of the minor and more polar sesquiterpenes with that of T-cadinol in the rat aorta. Like T-cadinol, the minor sesquiterpenes are more efficient in reducing K(+)-induced contractions than those induced by the alpha-adrenoceptor agonist phenylephrine, however, they were all less potent than T-cadinol.}},
author = {{Andersson, Maria and Bergendorff, Ola and Shan, Rudong and Zygmunt, Peter and Sterner, Olov}},
issn = {{0032-0943}},
keywords = {{Scented myrrh; Commiphora guidotti; Burseraceae; sesquiterpenes; T-cadinol; smooth muscle relaxant}},
language = {{eng}},
number = {{3}},
pages = {{251--254}},
publisher = {{Georg Thieme Verlag}},
series = {{Planta Medica}},
title = {{Minor components with smooth muscle relaxing properties from scented myrrh (Commiphora guidotti)}},
url = {{http://dx.doi.org/10.1055/s-2006-957665}},
doi = {{10.1055/s-2006-957665}},
volume = {{63}},
year = {{1997}},
}