Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Furanocoumarins with affinity to brain benzodiazepine receptors in vitro

Bergendorff, Ola LU ; Dekermendjian, Kim ; Nielsen, Mogens ; Shan, Rudong ; Witt, Robin ; Ai, Jinglu and Sterner, Olov LU (1997) In Phytochemistry 44(6). p.1121-1124
Abstract
Eight furanocoumarins were isolated from a methanol extract of dried roots of Angelica dahurica. One of these, phellopterin, strongly (IC50 = 0.36 microM) inhibits the binding of [3H]diazepam to central nervous system benzodiazepine receptors in vitro, while the others, despite their structural similarities with phellopterin, are considerably less active.
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Phytochemistry
volume
44
issue
6
pages
1121 - 1124
publisher
Elsevier
external identifiers
  • pmid:9055449
  • scopus:0031106566
ISSN
0031-9422
DOI
10.1016/S0031-9422(96)00703-0
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)
id
51d63fe0-575d-48d9-aed5-77bac9c4232c (old id 1111949)
date added to LUP
2016-04-01 16:33:46
date last changed
2022-04-22 22:56:28
@article{51d63fe0-575d-48d9-aed5-77bac9c4232c,
  abstract     = {{Eight furanocoumarins were isolated from a methanol extract of dried roots of Angelica dahurica. One of these, phellopterin, strongly (IC50 = 0.36 microM) inhibits the binding of [3H]diazepam to central nervous system benzodiazepine receptors in vitro, while the others, despite their structural similarities with phellopterin, are considerably less active.}},
  author       = {{Bergendorff, Ola and Dekermendjian, Kim and Nielsen, Mogens and Shan, Rudong and Witt, Robin and Ai, Jinglu and Sterner, Olov}},
  issn         = {{0031-9422}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{1121--1124}},
  publisher    = {{Elsevier}},
  series       = {{Phytochemistry}},
  title        = {{Furanocoumarins with affinity to brain benzodiazepine receptors in vitro}},
  url          = {{http://dx.doi.org/10.1016/S0031-9422(96)00703-0}},
  doi          = {{10.1016/S0031-9422(96)00703-0}},
  volume       = {{44}},
  year         = {{1997}},
}