Do BRCA1 mutations affect the ability to breast feed? Significantly shorter length of breast feeding among BRCA1 mutation carriers compared with their unaffected relatives.
Jernström, Helena LU ; Johannsson, L ; Borg, Åke LU and Olsson, Håkan LU
(1998)
In Breast
7(6).
p.320-324
- Abstract
- The difference in length of breast feeding between women with a BRCA 1 mutation and their unaffected relatives was investigated. Fifty women belonging to a family with a known BRCA1 mutation had themselves undergone testing and each had given birth to at least one child. Women with BRCA1 mutation breast-fed their first infant for a significantly shorter period (P = 0.048) and the second and third infants for a non-significantly shorter time than their unaffected relatives. Computing a mean breast-feeding time per child based on the first three infants and also taking birth year of the mother and smoking into account, having a BRCA1 mutation was associated with a significantly shorter time of breast-feeding (P = 0.034), and so was smoking... (More)
- The difference in length of breast feeding between women with a BRCA 1 mutation and their unaffected relatives was investigated. Fifty women belonging to a family with a known BRCA1 mutation had themselves undergone testing and each had given birth to at least one child. Women with BRCA1 mutation breast-fed their first infant for a significantly shorter period (P = 0.048) and the second and third infants for a non-significantly shorter time than their unaffected relatives. Computing a mean breast-feeding time per child based on the first three infants and also taking birth year of the mother and smoking into account, having a BRCA1 mutation was associated with a significantly shorter time of breast-feeding (P = 0.034), and so was smoking (P = 0.001), but birth year of the woman did not significantly influence length of breast-feeding. Seventy-five per cent of the assessable women with a BRCA1 mutation stopped breast-feeding owing to little or no milk production compared with 36% of the non-carriers OR = 5.3 (CI 95% 1.1–22.1) and (P = 0.02). Our finding may reflect a disturbed differentiation of the breast tissue in women with BRCA1 mutations. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1113129
- author
- Jernström, Helena
LU
; Johannsson, L
; Borg, Åke
LU
and Olsson, Håkan
LU
- organization
- publishing date
- 1998
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Breast
- volume
- 7
- issue
- 6
- pages
- 320 - 324
- publisher
- Churchill Livingstone
- external identifiers
-
- scopus:0032456403
- ISSN
- 1532-3080
- DOI
- 10.1016/S0960-9776(98)90074-1
- language
- English
- LU publication?
- yes
- id
- fff6180d-24ec-4e71-9683-f43830cc29ee (old id 1113129)
- date added to LUP
- 2016-04-01 15:30:01
- date last changed
- 2022-01-28 05:38:12
@article{fff6180d-24ec-4e71-9683-f43830cc29ee,
abstract = {{The difference in length of breast feeding between women with a BRCA 1 mutation and their unaffected relatives was investigated. Fifty women belonging to a family with a known BRCA1 mutation had themselves undergone testing and each had given birth to at least one child. Women with BRCA1 mutation breast-fed their first infant for a significantly shorter period (P = 0.048) and the second and third infants for a non-significantly shorter time than their unaffected relatives. Computing a mean breast-feeding time per child based on the first three infants and also taking birth year of the mother and smoking into account, having a BRCA1 mutation was associated with a significantly shorter time of breast-feeding (P = 0.034), and so was smoking (P = 0.001), but birth year of the woman did not significantly influence length of breast-feeding. Seventy-five per cent of the assessable women with a BRCA1 mutation stopped breast-feeding owing to little or no milk production compared with 36% of the non-carriers OR = 5.3 (CI 95% 1.1–22.1) and (P = 0.02). Our finding may reflect a disturbed differentiation of the breast tissue in women with BRCA1 mutations.}},
author = {{Jernström, Helena and Johannsson, L and Borg, Åke and Olsson, Håkan}},
issn = {{1532-3080}},
language = {{eng}},
number = {{6}},
pages = {{320--324}},
publisher = {{Churchill Livingstone}},
series = {{Breast}},
title = {{Do BRCA1 mutations affect the ability to breast feed? Significantly shorter length of breast feeding among BRCA1 mutation carriers compared with their unaffected relatives.}},
url = {{http://dx.doi.org/10.1016/S0960-9776(98)90074-1}},
doi = {{10.1016/S0960-9776(98)90074-1}},
volume = {{7}},
year = {{1998}},
}