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Evaluation of attenuation corrections using Monte Carlo simulated lung SPECT

Gustafsson, A; Bake, B; Jacobsson, L; Johansson, A; Ljungberg, Michael LU and Moonen, M (1998) In Physics in Medicine and Biology 43(8). p.2325-2336
Abstract
SPECT (single photon emission computed tomography) images are distorted by photon attenuation. The effect is complex in the thoracic region due to different tissue densities. This study compares the effect on the image homogeneity of two different methods of attenuation correction in lung SPECT; one pre-processing and one post-processing method. This study also investigates the impact of attenuation correction parameters such as lung contour, body contour, density of the lung tissue and effective attenuation coefficient. The Monte Carlo technique was used to simulate SPECT studies of a digital thorax phantom containing a homogeneous activity distribution in the lung. Homogeneity in reconstructed images was calculated as the coefficient of... (More)
SPECT (single photon emission computed tomography) images are distorted by photon attenuation. The effect is complex in the thoracic region due to different tissue densities. This study compares the effect on the image homogeneity of two different methods of attenuation correction in lung SPECT; one pre-processing and one post-processing method. This study also investigates the impact of attenuation correction parameters such as lung contour, body contour, density of the lung tissue and effective attenuation coefficient. The Monte Carlo technique was used to simulate SPECT studies of a digital thorax phantom containing a homogeneous activity distribution in the lung. Homogeneity in reconstructed images was calculated as the coefficient of variation (CV). The isolated effect of the attenuation correction was assessed by normalizing pixel values from the attenuation corrected lung by pixel values from the lung with no attenuation effects. Results show that the CV decreased from 12.8% with no attenuation correction to 4.4% using the post-processing method and true densities in the thoracic region. The impact of variations in the definition of the body contour was found to be marginal while the corresponding effect of variations in the lung contour was substantial (Less)
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organization
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Contribution to journal
publication status
published
subject
in
Physics in Medicine and Biology
volume
43
issue
8
pages
2325 - 2336
publisher
IOP Publishing
external identifiers
  • scopus:0031875528
ISSN
1361-6560
DOI
10.1088/0031-9155/43/8/023
language
English
LU publication?
yes
id
f17a09b6-7783-4c64-8cd1-38d2f4556eb3 (old id 1113372)
date added to LUP
2008-07-14 17:04:06
date last changed
2017-01-01 04:26:40
@article{f17a09b6-7783-4c64-8cd1-38d2f4556eb3,
  abstract     = {SPECT (single photon emission computed tomography) images are distorted by photon attenuation. The effect is complex in the thoracic region due to different tissue densities. This study compares the effect on the image homogeneity of two different methods of attenuation correction in lung SPECT; one pre-processing and one post-processing method. This study also investigates the impact of attenuation correction parameters such as lung contour, body contour, density of the lung tissue and effective attenuation coefficient. The Monte Carlo technique was used to simulate SPECT studies of a digital thorax phantom containing a homogeneous activity distribution in the lung. Homogeneity in reconstructed images was calculated as the coefficient of variation (CV). The isolated effect of the attenuation correction was assessed by normalizing pixel values from the attenuation corrected lung by pixel values from the lung with no attenuation effects. Results show that the CV decreased from 12.8% with no attenuation correction to 4.4% using the post-processing method and true densities in the thoracic region. The impact of variations in the definition of the body contour was found to be marginal while the corresponding effect of variations in the lung contour was substantial},
  author       = {Gustafsson, A and Bake, B and Jacobsson, L and Johansson, A and Ljungberg, Michael and Moonen, M},
  issn         = {1361-6560},
  language     = {eng},
  number       = {8},
  pages        = {2325--2336},
  publisher    = {IOP Publishing},
  series       = {Physics in Medicine and Biology},
  title        = {Evaluation of attenuation corrections using Monte Carlo simulated lung SPECT},
  url          = {http://dx.doi.org/10.1088/0031-9155/43/8/023},
  volume       = {43},
  year         = {1998},
}