Lung transplantation at the University of Lund 1990-1995. Analysis of the first 39 consecutive patients
(1998) In Scandinavian Cardiovascular Journal 32(1). p.23-28- Abstract
- Between 1990 and 1995 39 patients were lung transplanted at the University Hospital in Lund. This is a retrospective review of survival and lung function in these patients. There were 17 single-lung transplants (SLT), 21 double-lung transplants (DLT) and 1 heart-lung transplant (HLT). Seven patients died during the period, giving an overall survival of 82%. One-year survival according to Kaplan-Meier survival analysis was 87%, and 2-year survival was 83%. Vital capacity and forced expiratory volume in 1 s (FEV1) 1 year after transplantation were 91% and 100% of predicted, respectively, in the DLT group and 60% and 50% in the SLT group. Bronchiolitis obliterans syndrome (BOS) developed in 11 of the 35 patients (31%) surviving more than 6... (More)
- Between 1990 and 1995 39 patients were lung transplanted at the University Hospital in Lund. This is a retrospective review of survival and lung function in these patients. There were 17 single-lung transplants (SLT), 21 double-lung transplants (DLT) and 1 heart-lung transplant (HLT). Seven patients died during the period, giving an overall survival of 82%. One-year survival according to Kaplan-Meier survival analysis was 87%, and 2-year survival was 83%. Vital capacity and forced expiratory volume in 1 s (FEV1) 1 year after transplantation were 91% and 100% of predicted, respectively, in the DLT group and 60% and 50% in the SLT group. Bronchiolitis obliterans syndrome (BOS) developed in 11 of the 35 patients (31%) surviving more than 6 months, 2/21 in the DLT group and 8/13 in the SLT group and in the patient with HLT. The median time until detection of BOS was 11 months after the operation (range 6-18 months). Working capacity 1 year after transplantation was 60% of predicted in the DLT group and 47% of predicted in the SLT group. Ventilatory capacity was no longer function limiting. Lung transplantation today is a therapeutic option with a good medium-term survival and good functional results in selected patients with severe lung disease. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1113939
- author
- Eriksson, Leif LU ; Steen, Stig LU ; Koul, Bansi LU ; Mared, Lena LU and Solem, Jan Otto LU
- organization
- publishing date
- 1998
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Cardiovascular Journal
- volume
- 32
- issue
- 1
- pages
- 23 - 28
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:9536502
- scopus:0031881974
- ISSN
- 1651-2006
- DOI
- 10.1080/14017439850140300
- language
- English
- LU publication?
- yes
- id
- 2e6757af-5135-417c-ad7b-35401f99036d (old id 1113939)
- date added to LUP
- 2016-04-01 17:09:02
- date last changed
- 2022-01-29 00:44:35
@article{2e6757af-5135-417c-ad7b-35401f99036d, abstract = {{Between 1990 and 1995 39 patients were lung transplanted at the University Hospital in Lund. This is a retrospective review of survival and lung function in these patients. There were 17 single-lung transplants (SLT), 21 double-lung transplants (DLT) and 1 heart-lung transplant (HLT). Seven patients died during the period, giving an overall survival of 82%. One-year survival according to Kaplan-Meier survival analysis was 87%, and 2-year survival was 83%. Vital capacity and forced expiratory volume in 1 s (FEV1) 1 year after transplantation were 91% and 100% of predicted, respectively, in the DLT group and 60% and 50% in the SLT group. Bronchiolitis obliterans syndrome (BOS) developed in 11 of the 35 patients (31%) surviving more than 6 months, 2/21 in the DLT group and 8/13 in the SLT group and in the patient with HLT. The median time until detection of BOS was 11 months after the operation (range 6-18 months). Working capacity 1 year after transplantation was 60% of predicted in the DLT group and 47% of predicted in the SLT group. Ventilatory capacity was no longer function limiting. Lung transplantation today is a therapeutic option with a good medium-term survival and good functional results in selected patients with severe lung disease.}}, author = {{Eriksson, Leif and Steen, Stig and Koul, Bansi and Mared, Lena and Solem, Jan Otto}}, issn = {{1651-2006}}, language = {{eng}}, number = {{1}}, pages = {{23--28}}, publisher = {{Taylor & Francis}}, series = {{Scandinavian Cardiovascular Journal}}, title = {{Lung transplantation at the University of Lund 1990-1995. Analysis of the first 39 consecutive patients}}, url = {{http://dx.doi.org/10.1080/14017439850140300}}, doi = {{10.1080/14017439850140300}}, volume = {{32}}, year = {{1998}}, }