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Contribution of plasma-derived molecules to mucosal immune defence, disease and repair in the airways

Persson, Carl LU ; Erjefält, Jonas LU ; Greiff, Lennart LU ; Erjefalt, I ; Korsgren, Magnus LU ; Linden, M ; Sundler, Frank LU ; Andersson, M and Svensson, Christer LU (1998) In Scandinavian Journal of Immunology 47(4). p.302-313
Abstract
This review discusses recent observations, in health and disease, on the release and distribution of plasma-derived molecules in the airway mucosa. Briefly, the new data on airway mucosal exudation mechanisms suggest that the protein systems of plasma contribute significantly to the mucosal biology, not only in injured airways but also in such mildly inflamed airways that lack oedema and exhibit no sign of epithelial derangement. Plasma as a source of pluripotent growth factor, adhesive, leucocyte-activating, etc., molecules may deserve a prominent position in schemes that claim to illustrate immunological and inflammatory mechanisms of the airway mucosa in vivo.
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author
; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Scandinavian Journal of Immunology
volume
47
issue
4
pages
302 - 313
publisher
Wiley-Blackwell
external identifiers
  • pmid:9600311
  • scopus:0031966572
ISSN
1365-3083
DOI
10.1046/j.1365-3083.1998.00317.x
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Airway Inflammation and Immunology (013212038), Neuroendocrine Cell Biology (013212008), Division of Clinical Chemistry and Pharmacology (013250300), Otorhinolaryngology (Lund) (013044000)
id
fab30e99-7564-4932-a39b-1ced3331d6c1 (old id 1113969)
date added to LUP
2016-04-01 17:10:45
date last changed
2022-01-29 00:55:27
@article{fab30e99-7564-4932-a39b-1ced3331d6c1,
  abstract     = {{This review discusses recent observations, in health and disease, on the release and distribution of plasma-derived molecules in the airway mucosa. Briefly, the new data on airway mucosal exudation mechanisms suggest that the protein systems of plasma contribute significantly to the mucosal biology, not only in injured airways but also in such mildly inflamed airways that lack oedema and exhibit no sign of epithelial derangement. Plasma as a source of pluripotent growth factor, adhesive, leucocyte-activating, etc., molecules may deserve a prominent position in schemes that claim to illustrate immunological and inflammatory mechanisms of the airway mucosa in vivo.}},
  author       = {{Persson, Carl and Erjefält, Jonas and Greiff, Lennart and Erjefalt, I and Korsgren, Magnus and Linden, M and Sundler, Frank and Andersson, M and Svensson, Christer}},
  issn         = {{1365-3083}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{302--313}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Scandinavian Journal of Immunology}},
  title        = {{Contribution of plasma-derived molecules to mucosal immune defence, disease and repair in the airways}},
  url          = {{http://dx.doi.org/10.1046/j.1365-3083.1998.00317.x}},
  doi          = {{10.1046/j.1365-3083.1998.00317.x}},
  volume       = {{47}},
  year         = {{1998}},
}