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Quality assessment of localization technique performance in small volume in vivo 1H MR spectroscopy

Björkman-Burtscher, Isabella LU ; Johansson, Edvin LU ; Holtås, Stig LU and Ståhlberg, Freddy LU (1999) In Magnetic Resonance Imaging 17(10). p.1511-1519
Abstract
A new phantom and evaluation method for experimental evaluation of 1H-magnetic resonance spectroscopy single volume localization techniques regarding signal contamination (C), defined as the part of the signal originating outside the volume of interest, is presented. The quality assessment method is based on a spherical phantom with an oil/water interface in order to reduce susceptibility effects, and applied for stimulated-echo acquisition method (STEAM) and spin-echo (SE) sequences, echo times of 270, 135, and 10 ms, and cubic volumes of interest (VOI) of 1(3), 1.5(3), 2(3), 2.5(3), and 3(3) cm3. To be able to mimic measurements of the contamination in three dimensions the physical gradients representing the three orthogonal directions... (More)
A new phantom and evaluation method for experimental evaluation of 1H-magnetic resonance spectroscopy single volume localization techniques regarding signal contamination (C), defined as the part of the signal originating outside the volume of interest, is presented. The quality assessment method is based on a spherical phantom with an oil/water interface in order to reduce susceptibility effects, and applied for stimulated-echo acquisition method (STEAM) and spin-echo (SE) sequences, echo times of 270, 135, and 10 ms, and cubic volumes of interest (VOI) of 1(3), 1.5(3), 2(3), 2.5(3), and 3(3) cm3. To be able to mimic measurements of the contamination in three dimensions the physical gradients representing the three orthogonal directions for slice selection were shifted in the pulse sequences. Contamination values in one dimension differed between 6.5% and 8.4% in SE sequences, and between 0.7% and 13.8% in STEAM sequences. In STEAM sequences a decrease of C with increasing VOI size was observed while SE sequences showed comparable C values for the different VOI sizes tested. The total contamination in three dimensions were 19% and 18% in SE and STEAM sequences with a TE of 270 ms, and 7% in a STEAM sequence with a TE of 10 ms, respectively. The presented evaluation method is easily applied to the new phantom and showed high reproducibility. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Proton MRS, Phantom, Localization techniques, Quality assessment
in
Magnetic Resonance Imaging
volume
17
issue
10
pages
1511 - 1519
publisher
Elsevier
external identifiers
  • pmid:10610000
  • scopus:0032729884
ISSN
1873-5894
DOI
10.1016/S0730-725X(99)00076-4
language
English
LU publication?
yes
id
6445574f-6969-4297-9dcd-ce5f0d379cd5 (old id 1114718)
date added to LUP
2008-07-04 15:36:59
date last changed
2017-06-18 03:43:31
@article{6445574f-6969-4297-9dcd-ce5f0d379cd5,
  abstract     = {A new phantom and evaluation method for experimental evaluation of 1H-magnetic resonance spectroscopy single volume localization techniques regarding signal contamination (C), defined as the part of the signal originating outside the volume of interest, is presented. The quality assessment method is based on a spherical phantom with an oil/water interface in order to reduce susceptibility effects, and applied for stimulated-echo acquisition method (STEAM) and spin-echo (SE) sequences, echo times of 270, 135, and 10 ms, and cubic volumes of interest (VOI) of 1(3), 1.5(3), 2(3), 2.5(3), and 3(3) cm3. To be able to mimic measurements of the contamination in three dimensions the physical gradients representing the three orthogonal directions for slice selection were shifted in the pulse sequences. Contamination values in one dimension differed between 6.5% and 8.4% in SE sequences, and between 0.7% and 13.8% in STEAM sequences. In STEAM sequences a decrease of C with increasing VOI size was observed while SE sequences showed comparable C values for the different VOI sizes tested. The total contamination in three dimensions were 19% and 18% in SE and STEAM sequences with a TE of 270 ms, and 7% in a STEAM sequence with a TE of 10 ms, respectively. The presented evaluation method is easily applied to the new phantom and showed high reproducibility.},
  author       = {Björkman-Burtscher, Isabella and Johansson, Edvin and Holtås, Stig and Ståhlberg, Freddy},
  issn         = {1873-5894},
  keyword      = {Proton MRS,Phantom,Localization techniques,Quality assessment},
  language     = {eng},
  number       = {10},
  pages        = {1511--1519},
  publisher    = {Elsevier},
  series       = {Magnetic Resonance Imaging},
  title        = {Quality assessment of localization technique performance in small volume in vivo 1H MR spectroscopy},
  url          = {http://dx.doi.org/10.1016/S0730-725X(99)00076-4},
  volume       = {17},
  year         = {1999},
}