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Image artifacts due to a time-varying contrast medium concentration in 3D contrast-enhanced MRA

Svensson, Jonas LU ; Petersson, J Stefan LU ; Ståhlberg, Freddy LU ; Larsson, Elna-Marie LU ; Leander, Peter LU and Olsson, Lars E LU (1999) In Journal of Magnetic Resonance Imaging 10(6). p.919-928
Abstract
The purpose of this work was to study image effects due to time-varying contrast medium concentration in contrast-enhanced three dimensional (3D) magnetic resonance angiography (MRA) images. Two different simulation models (1D and 3D) and two different contrast medium variation schemes were used. Phantom measurements were also performed. Experiments were performed for several different bolus timings. Similar sequence and image object parameters were used in both simulations and measurements (TE/TR 2. 1/7.8 mses, flip angle 30 degrees, T1/T2 1200-80/150-40 msec, flow velocity 100 cm/sec). A small variation in bolus timing yielded large variations in the appearance of the image effects, especially if the center of k-space was sampled in the... (More)
The purpose of this work was to study image effects due to time-varying contrast medium concentration in contrast-enhanced three dimensional (3D) magnetic resonance angiography (MRA) images. Two different simulation models (1D and 3D) and two different contrast medium variation schemes were used. Phantom measurements were also performed. Experiments were performed for several different bolus timings. Similar sequence and image object parameters were used in both simulations and measurements (TE/TR 2. 1/7.8 mses, flip angle 30 degrees, T1/T2 1200-80/150-40 msec, flow velocity 100 cm/sec). A small variation in bolus timing yielded large variations in the appearance of the image effects, especially if the center of k-space was sampled in the vicinity of rapid contrast medium concentration variation. For a typical bolus injection in a patient, a severe signal loss but only minor ringing and edge artifacts appeared if the bolus injection was poorly timed. Effects of pulsatile flow were minor. The 3D model proved to be a useful tool in these studies. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
contrast medium, angiography, magnetic resonance, artifacts, simulations
in
Journal of Magnetic Resonance Imaging
volume
10
issue
6
pages
919 - 928
publisher
John Wiley & Sons
external identifiers
  • pmid:10581504
  • scopus:0032722743
ISSN
1522-2586
DOI
10.1002/(SICI)1522-2586(199912)10:6<919::AID-JMRI3>3.0.CO;2-W
language
English
LU publication?
yes
id
9bb64f5c-9d84-49e5-822c-95b825e6dbcb (old id 1114722)
alternative location
http://www3.interscience.wiley.com/cgi-bin/fulltext/67502017/PDFSTART
date added to LUP
2008-07-04 15:40:34
date last changed
2017-01-01 04:54:52
@article{9bb64f5c-9d84-49e5-822c-95b825e6dbcb,
  abstract     = {The purpose of this work was to study image effects due to time-varying contrast medium concentration in contrast-enhanced three dimensional (3D) magnetic resonance angiography (MRA) images. Two different simulation models (1D and 3D) and two different contrast medium variation schemes were used. Phantom measurements were also performed. Experiments were performed for several different bolus timings. Similar sequence and image object parameters were used in both simulations and measurements (TE/TR 2. 1/7.8 mses, flip angle 30 degrees, T1/T2 1200-80/150-40 msec, flow velocity 100 cm/sec). A small variation in bolus timing yielded large variations in the appearance of the image effects, especially if the center of k-space was sampled in the vicinity of rapid contrast medium concentration variation. For a typical bolus injection in a patient, a severe signal loss but only minor ringing and edge artifacts appeared if the bolus injection was poorly timed. Effects of pulsatile flow were minor. The 3D model proved to be a useful tool in these studies.},
  author       = {Svensson, Jonas and Petersson, J Stefan and Ståhlberg, Freddy and Larsson, Elna-Marie and Leander, Peter and Olsson, Lars E},
  issn         = {1522-2586},
  keyword      = {contrast medium,angiography,magnetic resonance,artifacts,simulations},
  language     = {eng},
  number       = {6},
  pages        = {919--928},
  publisher    = {John Wiley & Sons},
  series       = {Journal of Magnetic Resonance Imaging},
  title        = {Image artifacts due to a time-varying contrast medium concentration in 3D contrast-enhanced MRA},
  url          = {http://dx.doi.org/10.1002/(SICI)1522-2586(199912)10:6<919::AID-JMRI3>3.0.CO;2-W},
  volume       = {10},
  year         = {1999},
}