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Incomplete incorporation of morselized and impacted autologous bone graft: a histological study in 4 intracorporally grafted lumbar fractures

Tägil, Magnus LU ; Johnsson, Ragnar LU ; Strömqvist, Björn LU and Aspenberg, Per LU (1999) In Acta Orthopaedica Scandinavica 70(6). p.555-558
Abstract
Morselized and impacted bone allografts are used successfully in hip and knee revisions, but experiments using bone chambers indicate that impaction actually can delay ingrowth of new bone into a graft. To understand the remodeling and incorporation process of morselized and impacted grafts, we studied the incorporation of morselized impacted autografts in lumbar fractures histologically. 4 patients were operated on for Th XII-LI fractures. The fractures were stabilized by VSP plates and transpedicular screws in the vertebrae above and below the fractured one. Autologous bone graft was packed into the fractured vertebral body through one of the pedicles. After 18-20 months, the plates were removed and biopsies were obtained from various... (More)
Morselized and impacted bone allografts are used successfully in hip and knee revisions, but experiments using bone chambers indicate that impaction actually can delay ingrowth of new bone into a graft. To understand the remodeling and incorporation process of morselized and impacted grafts, we studied the incorporation of morselized impacted autografts in lumbar fractures histologically. 4 patients were operated on for Th XII-LI fractures. The fractures were stabilized by VSP plates and transpedicular screws in the vertebrae above and below the fractured one. Autologous bone graft was packed into the fractured vertebral body through one of the pedicles. After 18-20 months, the plates were removed and biopsies were obtained from various locations in the fractured vertebra. All fractures were at this time clinically and radiographically healed. Histologically, in all cases, large areas of the autograft in the vertebral body were unvascularized and partially or entirely necrotic. As with morselized bone in hip revisions, evaluation of graft incorporation requires histological examination. Full osseous incorporation of a graft is not always necessary for a good clinical result. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Orthopaedica Scandinavica
volume
70
issue
6
pages
555 - 558
publisher
Taylor & Francis
external identifiers
  • pmid:10665718
  • scopus:0033380539
ISSN
0001-6470
DOI
10.3109/17453679908997841
language
English
LU publication?
yes
id
5ae6789f-aa47-477a-8b2a-8757d7b33ace (old id 1115078)
date added to LUP
2008-07-07 13:52:44
date last changed
2017-02-26 04:19:23
@article{5ae6789f-aa47-477a-8b2a-8757d7b33ace,
  abstract     = {Morselized and impacted bone allografts are used successfully in hip and knee revisions, but experiments using bone chambers indicate that impaction actually can delay ingrowth of new bone into a graft. To understand the remodeling and incorporation process of morselized and impacted grafts, we studied the incorporation of morselized impacted autografts in lumbar fractures histologically. 4 patients were operated on for Th XII-LI fractures. The fractures were stabilized by VSP plates and transpedicular screws in the vertebrae above and below the fractured one. Autologous bone graft was packed into the fractured vertebral body through one of the pedicles. After 18-20 months, the plates were removed and biopsies were obtained from various locations in the fractured vertebra. All fractures were at this time clinically and radiographically healed. Histologically, in all cases, large areas of the autograft in the vertebral body were unvascularized and partially or entirely necrotic. As with morselized bone in hip revisions, evaluation of graft incorporation requires histological examination. Full osseous incorporation of a graft is not always necessary for a good clinical result.},
  author       = {Tägil, Magnus and Johnsson, Ragnar and Strömqvist, Björn and Aspenberg, Per},
  issn         = {0001-6470},
  language     = {eng},
  number       = {6},
  pages        = {555--558},
  publisher    = {Taylor & Francis},
  series       = {Acta Orthopaedica Scandinavica},
  title        = {Incomplete incorporation of morselized and impacted autologous bone graft: a histological study in 4 intracorporally grafted lumbar fractures},
  url          = {http://dx.doi.org/10.3109/17453679908997841},
  volume       = {70},
  year         = {1999},
}