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New world, but not Old World, monkeys carry several genes encoding beta-microseminoprotein

Makinen, M ; Valtonen-André, Camilla LU and Lundwall, Åke LU (1999) In European Journal of Biochemistry 264(2). p.407-414
Abstract
It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of... (More)
It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of interspersed repeats, on average 29% of the introns consist of Alu repeats. A phylogenetic analysis demonstrated that the genes probably arose in New World monkeys after the separation from Old World primates. (Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
mucous, evolution, prostate, semen
in
European Journal of Biochemistry
volume
264
issue
2
pages
407 - 414
publisher
Wiley-Blackwell
external identifiers
  • pmid:10491085
  • scopus:0033199569
ISSN
0014-2956
language
English
LU publication?
yes
id
c77e352f-1eed-4f51-8c67-ad247f87b6ab (old id 1115112)
alternative location
http://www.ingentaconnect.com/content/bsc/ejb/1999/00000264/00000002/art00614
date added to LUP
2016-04-01 16:41:49
date last changed
2022-01-28 21:28:37
@article{c77e352f-1eed-4f51-8c67-ad247f87b6ab,
  abstract     = {{It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of interspersed repeats, on average 29% of the introns consist of Alu repeats. A phylogenetic analysis demonstrated that the genes probably arose in New World monkeys after the separation from Old World primates.}},
  author       = {{Makinen, M and Valtonen-André, Camilla and Lundwall, Åke}},
  issn         = {{0014-2956}},
  keywords     = {{mucous; evolution; prostate; semen}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{407--414}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{European Journal of Biochemistry}},
  title        = {{New world, but not Old World, monkeys carry several genes encoding beta-microseminoprotein}},
  url          = {{http://www.ingentaconnect.com/content/bsc/ejb/1999/00000264/00000002/art00614}},
  volume       = {{264}},
  year         = {{1999}},
}