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New world, but not Old World, monkeys carry several genes encoding beta-microseminoprotein

Makinen, M; Valtonen-André, Camilla LU and Lundwall, Åke LU (1999) In European Journal of Biochemistry 264(2). p.407-414
Abstract
It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of... (More)
It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of interspersed repeats, on average 29% of the introns consist of Alu repeats. A phylogenetic analysis demonstrated that the genes probably arose in New World monkeys after the separation from Old World primates. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
mucous, evolution, prostate, semen
in
European Journal of Biochemistry
volume
264
issue
2
pages
407 - 414
publisher
Wiley-Blackwell
external identifiers
  • pmid:10491085
  • scopus:0033199569
ISSN
0014-2956
language
English
LU publication?
yes
id
c77e352f-1eed-4f51-8c67-ad247f87b6ab (old id 1115112)
alternative location
http://www.ingentaconnect.com/content/bsc/ejb/1999/00000264/00000002/art00614
date added to LUP
2008-07-07 14:15:03
date last changed
2017-01-01 07:12:31
@article{c77e352f-1eed-4f51-8c67-ad247f87b6ab,
  abstract     = {It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of interspersed repeats, on average 29% of the introns consist of Alu repeats. A phylogenetic analysis demonstrated that the genes probably arose in New World monkeys after the separation from Old World primates.},
  author       = {Makinen, M and Valtonen-André, Camilla and Lundwall, Åke},
  issn         = {0014-2956},
  keyword      = {mucous,evolution,prostate,semen},
  language     = {eng},
  number       = {2},
  pages        = {407--414},
  publisher    = {Wiley-Blackwell},
  series       = {European Journal of Biochemistry},
  title        = {New world, but not Old World, monkeys carry several genes encoding beta-microseminoprotein},
  volume       = {264},
  year         = {1999},
}