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The effects of galvanic stimulation on the human vestibulo-ocular reflex

Karlberg, Mikael LU ; McGarvie, L; Magnusson, Måns LU ; Aw, S T and Halmagyi, G M (2000) In NeuroReport 11(17). p.3897-3901
Abstract
We studied the effects of 5 mA bilateral or unilateral, bipolar or monopolar, galvanic stimulation on the horizontal vestibulo-ocular reflex (hVOR) in six normal subjects during 0.01, 0.05, 0.1, 0.5 and 1 Hz yaw rotations and in two subjects during high-acceleration, low-amplitude yaw head rotations (head impulses). Bipolar galvanic stimulation induced horizontal nystagmus in all subjects and an asymmetry of the hVOR only during rotations below 0.1 Hz. Monopolar stimulation had no significant effect. The findings suggest that in humans galvanic stimulation affects those primary horizontal semicircular canal neurons that mediate the hVOR via indirect pathways through the velocity storage mechanism.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
NeuroReport
volume
11
issue
17
pages
3897 - 3901
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:11117511
  • scopus:0034722595
ISSN
1473-558X
language
English
LU publication?
yes
id
5269f1c1-7173-4a0c-b817-77d47abcfe45 (old id 1116512)
date added to LUP
2008-07-01 14:02:45
date last changed
2017-05-31 10:42:09
@article{5269f1c1-7173-4a0c-b817-77d47abcfe45,
  abstract     = {We studied the effects of 5 mA bilateral or unilateral, bipolar or monopolar, galvanic stimulation on the horizontal vestibulo-ocular reflex (hVOR) in six normal subjects during 0.01, 0.05, 0.1, 0.5 and 1 Hz yaw rotations and in two subjects during high-acceleration, low-amplitude yaw head rotations (head impulses). Bipolar galvanic stimulation induced horizontal nystagmus in all subjects and an asymmetry of the hVOR only during rotations below 0.1 Hz. Monopolar stimulation had no significant effect. The findings suggest that in humans galvanic stimulation affects those primary horizontal semicircular canal neurons that mediate the hVOR via indirect pathways through the velocity storage mechanism.},
  author       = {Karlberg, Mikael and McGarvie, L and Magnusson, Måns and Aw, S T and Halmagyi, G M},
  issn         = {1473-558X},
  language     = {eng},
  number       = {17},
  pages        = {3897--3901},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {NeuroReport},
  title        = {The effects of galvanic stimulation on the human vestibulo-ocular reflex},
  volume       = {11},
  year         = {2000},
}