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Detection of inter-atrial conduction defects with unfiltered signal-averaged P-wave ECG in patients with lone atrial fibrillation

Platonov, Pyotr LU ; Carlson, Jonas LU ; Ingemansson, Max LU ; Roijer, Anders LU ; Hansson, A; Chireikin, L V and Olsson, Bertil LU (2000) In Europace 2(1). p.32-41
Abstract
AIMS: To demonstrate a possible inter-atrial conduction delay in patients with lone paroxysmal atrial fibrillation (PAF) using 'unfiltered' signal-averaged P-wave ECG (PSAECG) and compare these results with those obtained with conventional filter settings. METHODS AND RESULTS: Twenty one patients with lone PAF and 20 healthy volunteers (control group) were enrolled in the study. An orthogonal lead surface ECG was high-pass filtered at 0.8 Hz, averaged with template matching, and combined into a spatial magnitude ('unfiltered' technique). Results were compared with conventionally filtered (40-300 Hz) PSAECG. The filtered technique revealed no differences in P-wave duration between the two groups (121 +/- 12 vs 128 +/- 15 ms, control and PAF... (More)
AIMS: To demonstrate a possible inter-atrial conduction delay in patients with lone paroxysmal atrial fibrillation (PAF) using 'unfiltered' signal-averaged P-wave ECG (PSAECG) and compare these results with those obtained with conventional filter settings. METHODS AND RESULTS: Twenty one patients with lone PAF and 20 healthy volunteers (control group) were enrolled in the study. An orthogonal lead surface ECG was high-pass filtered at 0.8 Hz, averaged with template matching, and combined into a spatial magnitude ('unfiltered' technique). Results were compared with conventionally filtered (40-300 Hz) PSAECG. The filtered technique revealed no differences in P-wave duration between the two groups (121 +/- 12 vs 128 +/- 15 ms, control and PAF groups respectively, ns). Double-peaked P-wave spatial magnitudes (interpeak distance >30 ms) were revealed in 11 of 21 PAF patients but only in two of 18 controls (P<0.01). The nadir in the spatial magnitude was located significantly later in the PAF group (114 +/- 13 vs 103 +/- 9 ms, P<0.01). CONCLUSION: 'Unfiltered' PSAECG revealed significant differences in orthogonal P-wave morphology in patients with lone PAF, indicating the possibility of an inter-atrial conduction delay, while conventional P-wave duration analysis failed to discriminate between the two groups. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Signal-averaged P-wave ECG, paroxysmal atrial fibrillation, inter-atrial conduction
in
Europace
volume
2
issue
1
pages
32 - 41
publisher
Oxford University Press
external identifiers
  • pmid:11227584
  • scopus:0033760028
ISSN
1532-2092
DOI
10.1053/eupc.1999.0072
language
English
LU publication?
yes
id
d2cdbd78-734d-409b-b1ca-a815d7c61efc (old id 1116590)
date added to LUP
2008-07-02 08:52:25
date last changed
2017-10-01 03:51:54
@article{d2cdbd78-734d-409b-b1ca-a815d7c61efc,
  abstract     = {AIMS: To demonstrate a possible inter-atrial conduction delay in patients with lone paroxysmal atrial fibrillation (PAF) using 'unfiltered' signal-averaged P-wave ECG (PSAECG) and compare these results with those obtained with conventional filter settings. METHODS AND RESULTS: Twenty one patients with lone PAF and 20 healthy volunteers (control group) were enrolled in the study. An orthogonal lead surface ECG was high-pass filtered at 0.8 Hz, averaged with template matching, and combined into a spatial magnitude ('unfiltered' technique). Results were compared with conventionally filtered (40-300 Hz) PSAECG. The filtered technique revealed no differences in P-wave duration between the two groups (121 +/- 12 vs 128 +/- 15 ms, control and PAF groups respectively, ns). Double-peaked P-wave spatial magnitudes (interpeak distance &gt;30 ms) were revealed in 11 of 21 PAF patients but only in two of 18 controls (P&lt;0.01). The nadir in the spatial magnitude was located significantly later in the PAF group (114 +/- 13 vs 103 +/- 9 ms, P&lt;0.01). CONCLUSION: 'Unfiltered' PSAECG revealed significant differences in orthogonal P-wave morphology in patients with lone PAF, indicating the possibility of an inter-atrial conduction delay, while conventional P-wave duration analysis failed to discriminate between the two groups.},
  author       = {Platonov, Pyotr and Carlson, Jonas and Ingemansson, Max and Roijer, Anders and Hansson, A and Chireikin, L V and Olsson, Bertil},
  issn         = {1532-2092},
  keyword      = {Signal-averaged P-wave ECG,paroxysmal atrial fibrillation,inter-atrial conduction},
  language     = {eng},
  number       = {1},
  pages        = {32--41},
  publisher    = {Oxford University Press},
  series       = {Europace},
  title        = {Detection of inter-atrial conduction defects with unfiltered signal-averaged P-wave ECG in patients with lone atrial fibrillation},
  url          = {http://dx.doi.org/10.1053/eupc.1999.0072},
  volume       = {2},
  year         = {2000},
}