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The Cell Physiology of Biphasic Insulin Secretion

Rorsman, Patrik LU ; Eliasson, Lena LU ; Renström, Erik LU ; Gromada, Jesper; Barg, Sebastian LU and Göpel, Sven LU (2000) In News in Physiological Sciences - Nips 15(2). p.72-77
Abstract
Glucose-stimulated insulin secretion consists of a transient first phase followed by a sustained second phase. Diabetes (type II) is associated with abnormalities in this release pattern. Here we review the evidence that biphasic insulin secretion reflects exocytosis of two functional subsets of secretory granules and the implications for diabetes.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
News in Physiological Sciences - Nips
volume
15
issue
2
pages
72 - 77
publisher
American Physiological Society
external identifiers
  • pmid:11390882
  • scopus:0034410505
ISSN
1522-161X
language
English
LU publication?
yes
id
9325aeca-d7fd-40ff-917a-1af7c6108303 (old id 1117031)
alternative location
http://physiologyonline.physiology.org/cgi/content/full/15/2/72
date added to LUP
2008-07-02 15:28:20
date last changed
2017-11-19 03:39:00
@article{9325aeca-d7fd-40ff-917a-1af7c6108303,
  abstract     = {Glucose-stimulated insulin secretion consists of a transient first phase followed by a sustained second phase. Diabetes (type II) is associated with abnormalities in this release pattern. Here we review the evidence that biphasic insulin secretion reflects exocytosis of two functional subsets of secretory granules and the implications for diabetes.},
  author       = {Rorsman, Patrik and Eliasson, Lena and Renström, Erik and Gromada, Jesper and Barg, Sebastian and Göpel, Sven},
  issn         = {1522-161X},
  language     = {eng},
  number       = {2},
  pages        = {72--77},
  publisher    = {American Physiological Society},
  series       = {News in Physiological Sciences - Nips},
  title        = {The Cell Physiology of Biphasic Insulin Secretion},
  volume       = {15},
  year         = {2000},
}